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A chemical and genetic approach to the mode of action of fumagillin.
Zhang Y, Yeh JR, Mara A, Ju R, Hines JF, Cirone P, Griesbach HL, Schneider I, Slusarski DC, Holley SA, Crews CM. Zhang Y, et al. Among authors: crews cm. Chem Biol. 2006 Sep;13(9):1001-9. doi: 10.1016/j.chembiol.2006.07.010. Chem Biol. 2006. PMID: 16984890 Free PMC article.
The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case Study.
Burslem GM, Smith BE, Lai AC, Jaime-Figueroa S, McQuaid DC, Bondeson DP, Toure M, Dong H, Qian Y, Wang J, Crew AP, Hines J, Crews CM. Burslem GM, et al. Among authors: crews cm. Cell Chem Biol. 2018 Jan 18;25(1):67-77.e3. doi: 10.1016/j.chembiol.2017.09.009. Epub 2017 Nov 9. Cell Chem Biol. 2018. PMID: 29129716 Free PMC article.
Lessons in PROTAC Design from Selective Degradation with a Promiscuous Warhead.
Bondeson DP, Smith BE, Burslem GM, Buhimschi AD, Hines J, Jaime-Figueroa S, Wang J, Hamman BD, Ishchenko A, Crews CM. Bondeson DP, et al. Among authors: crews cm. Cell Chem Biol. 2018 Jan 18;25(1):78-87.e5. doi: 10.1016/j.chembiol.2017.09.010. Epub 2017 Nov 9. Cell Chem Biol. 2018. PMID: 29129718 Free PMC article.
Targeted protein degradation: elements of PROTAC design.
Paiva SL, Crews CM. Paiva SL, et al. Among authors: crews cm. Curr Opin Chem Biol. 2019 Jun;50:111-119. doi: 10.1016/j.cbpa.2019.02.022. Epub 2019 Apr 17. Curr Opin Chem Biol. 2019. PMID: 31004963 Free PMC article. Review.
193 results