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Page 1
Identification of Dihydroorotate Dehydrogenase Inhibitors Using the Cell Painting Assay.
Schölermann B, Bonowski J, Grigalunas M, Burhop A, Xie Y, Hoock JGF, Liu J, Dow M, Nelson A, Nowak C, Pahl A, Sievers S, Ziegler S. Schölermann B, et al. Among authors: grigalunas m. Chembiochem. 2022 Nov 18;23(22):e202200475. doi: 10.1002/cbic.202200475. Epub 2022 Oct 13. Chembiochem. 2022. PMID: 36134475 Free PMC article.
The Pseudo-Natural Product Rhonin Targets RHOGDI.
Akbarzadeh M, Flegel J, Patil S, Shang E, Narayan R, Buchholzer M, Kazemein Jasemi NS, Grigalunas M, Krzyzanowski A, Abegg D, Shuster A, Potowski M, Karatas H, Karageorgis G, Mosaddeghzadeh N, Zischinsky ML, Merten C, Golz C, Brieger L, Strohmann C, Antonchick AP, Janning P, Adibekian A, Goody RS, Ahmadian MR, Ziegler S, Waldmann H. Akbarzadeh M, et al. Among authors: grigalunas m. Angew Chem Int Ed Engl. 2022 Apr 25;61(18):e202115193. doi: 10.1002/anie.202115193. Epub 2022 Mar 2. Angew Chem Int Ed Engl. 2022. PMID: 35170181 Free PMC article.
A highly enantioselective intramolecular 1,3-dipolar cycloaddition yields novel pseudo-natural product inhibitors of the Hedgehog signalling pathway.
Liu J, Zhang R, Mallick S, Patil S, Wientjens C, Flegel J, Krupp A, Strohmann C, Grassin C, Merten C, Pahl A, Grigalunas M, Waldmann H. Liu J, et al. Among authors: grigalunas m. Chem Sci. 2023 Jun 21;14(29):7936-7943. doi: 10.1039/d3sc01240a. eCollection 2023 Jul 26. Chem Sci. 2023. PMID: 37502335 Free PMC article.
Collective Synthesis of Sarpagine and Macroline Alkaloid-Inspired Compounds.
Aoyama H, Davies C, Liu J, Pahl A, Kirchhoff JL, Scheel R, Sievers S, Strohmann C, Grigalunas M, Waldmann H. Aoyama H, et al. Among authors: grigalunas m. Chemistry. 2024 Jan 22;30(5):e202303027. doi: 10.1002/chem.202303027. Epub 2023 Nov 29. Chemistry. 2024. PMID: 37755456
Synthetic Matching of Complex Monoterpene Indole Alkaloid Chemical Space.
Xie J, Pahl A, Krzyzanowski A, Krupp A, Liu J, Koska S, Schölermann B, Zhang R, Bonowski J, Sievers S, Strohmann C, Ziegler S, Grigalunas M, Waldmann H. Xie J, et al. Among authors: grigalunas m. Angew Chem Int Ed Engl. 2023 Nov 27;62(48):e202310222. doi: 10.1002/anie.202310222. Epub 2023 Oct 24. Angew Chem Int Ed Engl. 2023. PMID: 37818743
23 results