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Production and nonclinical evaluation of an autologous iPSC-derived platelet product for the iPLAT1 clinical trial.
Sugimoto N, Nakamura S, Shimizu S, Shigemasa A, Kanda J, Matsuyama N, Tanaka M, Hayashi T, Fuchizaki A, Nogawa M, Watanabe N, Okamoto S, Handa M, Sawaguchi A, Momose D, Koh KR, Tani Y, Takaori-Kondo A, Eto K. Sugimoto N, et al. Blood Adv. 2022 Dec 13;6(23):6056-6069. doi: 10.1182/bloodadvances.2022008512. Blood Adv. 2022. PMID: 36149941 Free PMC article.
Selective Inhibition of ADAM17 Efficiently Mediates Glycoprotein Ibα Retention During Ex Vivo Generation of Human Induced Pluripotent Stem Cell-Derived Platelets.
Hirata S, Murata T, Suzuki D, Nakamura S, Jono-Ohnishi R, Hirose H, Sawaguchi A, Nishimura S, Sugimoto N, Eto K. Hirata S, et al. Among authors: sugimoto n. Stem Cells Transl Med. 2017 Mar;6(3):720-730. doi: 10.5966/sctm.2016-0104. Epub 2016 Oct 5. Stem Cells Transl Med. 2017. PMID: 28297575 Free PMC article.
Turbulence Activates Platelet Biogenesis to Enable Clinical Scale Ex Vivo Production.
Ito Y, Nakamura S, Sugimoto N, Shigemori T, Kato Y, Ohno M, Sakuma S, Ito K, Kumon H, Hirose H, Okamoto H, Nogawa M, Iwasaki M, Kihara S, Fujio K, Matsumoto T, Higashi N, Hashimoto K, Sawaguchi A, Harimoto KI, Nakagawa M, Yamamoto T, Handa M, Watanabe N, Nishi E, Arai F, Nishimura S, Eto K. Ito Y, et al. Among authors: sugimoto n. Cell. 2018 Jul 26;174(3):636-648.e18. doi: 10.1016/j.cell.2018.06.011. Epub 2018 Jul 12. Cell. 2018. PMID: 30017246 Free article.
αIIbβ3 changes gears in MKs and platelets.
Sugimoto N, Eto K. Sugimoto N, et al. Blood. 2019 Apr 18;133(16):1700-1701. doi: 10.1182/blood-2019-01-896092. Blood. 2019. PMID: 31000515 Free article. No abstract available.
1,214 results