Hoffmann C - Search Results

1

β-arrestin1 and 2 exhibit distinct phosphorylation-dependent conformations when coupling to the same GPCR in living cells.

Haider RS, Matthees ESF, Drube J, Reichel M, Zabel U, Inoue A, Chevigné A, Krasel C, Deupi X, Hoffmann C. Haider RS, et al. Among authors: hoffmann c. Nat Commun. 2022 Sep 26;13(1):5638. doi: 10.1038/s41467-022-33307-8. Nat Commun. 2022. PMID: 36163356 Free PMC article.

2

A FlAsH-based FRET approach to determine G protein-coupled receptor activation in living cells.

Hoffmann C, Gaietta G, Bünemann M, Adams SR, Oberdorff-Maass S, Behr B, Vilardaga JP, Tsien RY, Ellisman MH, Lohse MJ. Hoffmann C, et al. Nat Methods. 2005 Mar;2(3):171-6. doi: 10.1038/nmeth742. Epub 2005 Feb 17. Nat Methods. 2005. PMID: 15782185

3

Agonist-selective, receptor-specific interaction of human P2Y receptors with beta-arrestin-1 and -2.

Hoffmann C, Ziegler N, Reiner S, Krasel C, Lohse MJ. Hoffmann C, et al. J Biol Chem. 2008 Nov 7;283(45):30933-41. doi: 10.1074/jbc.M801472200. Epub 2008 Aug 14. J Biol Chem. 2008. PMID: 18703513 Free PMC article.

4

Fluorescence resonance energy transfer analysis of alpha 2a-adrenergic receptor activation reveals distinct agonist-specific conformational changes.

Zürn A, Zabel U, Vilardaga JP, Schindelin H, Lohse MJ, Hoffmann C. Zürn A, et al. Among authors: hoffmann c. Mol Pharmacol. 2009 Mar;75(3):534-41. doi: 10.1124/mol.108.052399. Epub 2008 Dec 23. Mol Pharmacol. 2009. PMID: 19106230

5

Site-specific, orthogonal labeling of proteins in intact cells with two small biarsenical fluorophores.

Zürn A, Klenk C, Zabel U, Reiner S, Lohse MJ, Hoffmann C. Zürn A, et al. Among authors: hoffmann c. Bioconjug Chem. 2010 May 19;21(5):853-9. doi: 10.1021/bc900394j. Bioconjug Chem. 2010. PMID: 20429545

6

FRET-based sensors for the human M1-, M3-, and M5-acetylcholine receptors.

Ziegler N, Bätz J, Zabel U, Lohse MJ, Hoffmann C. Ziegler N, et al. Among authors: hoffmann c. Bioorg Med Chem. 2011 Feb 1;19(3):1048-54. doi: 10.1016/j.bmc.2010.07.060. Epub 2010 Jul 30. Bioorg Med Chem. 2011. PMID: 20716489

7

Comparison of the activation kinetics of the M3 acetylcholine receptor and a constitutively active mutant receptor in living cells.

Hoffmann C, Nuber S, Zabel U, Ziegler N, Winkler C, Hein P, Berlot CH, Bünemann M, Lohse MJ. Hoffmann C, et al. Mol Pharmacol. 2012 Aug;82(2):236-45. doi: 10.1124/mol.112.077578. Epub 2012 May 7. Mol Pharmacol. 2012. PMID: 22564786 Free PMC article.

8

Sequential inter- and intrasubunit rearrangements during activation of dimeric metabotropic glutamate receptor 1.

Hlavackova V, Zabel U, Frankova D, Bätz J, Hoffmann C, Prezeau L, Pin JP, Blahos J, Lohse MJ. Hlavackova V, et al. Among authors: hoffmann c. Sci Signal. 2012 Aug 14;5(237):ra59. doi: 10.1126/scisignal.2002720. Sci Signal. 2012. PMID: 22894836

9

The allosteric vestibule of a seven transmembrane helical receptor controls G-protein coupling.

Bock A, Merten N, Schrage R, Dallanoce C, Bätz J, Klöckner J, Schmitz J, Matera C, Simon K, Kebig A, Peters L, Müller A, Schrobang-Ley J, Tränkle C, Hoffmann C, De Amici M, Holzgrabe U, Kostenis E, Mohr K. Bock A, et al. Among authors: hoffmann c. Nat Commun. 2012;3:1044. doi: 10.1038/ncomms2028. Nat Commun. 2012. PMID: 22948826 Free PMC article.

10

Arrestin interactions with G protein-coupled receptors.

Lohse MJ, Hoffmann C. Lohse MJ, et al. Among authors: hoffmann c. Handb Exp Pharmacol. 2014;219:15-56. doi: 10.1007/978-3-642-41199-1_2. Handb Exp Pharmacol. 2014. PMID: 24292823

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