Alvarez JV - Search Results

1

In vivo metabolic imaging identifies lipid vulnerability in a preclinical model of Her2+/Neu breast cancer residual disease and recurrence.

Madonna MC, Duer JE, McKinney BJ, Sunassee ED, Crouch BT, Ilkayeva O, Hirschey MD, Alvarez JV, Ramanujam N. Madonna MC, et al. Among authors: alvarez jv. NPJ Breast Cancer. 2022 Sep 26;8(1):111. doi: 10.1038/s41523-022-00481-3. NPJ Breast Cancer. 2022. PMID: 36163365 Free PMC article.

2

Optical Imaging of Glucose Uptake and Mitochondrial Membrane Potential to Characterize Her2 Breast Tumor Metabolic Phenotypes.

Madonna MC, Fox DB, Crouch BT, Lee J, Zhu C, Martinez AF, Alvarez JV, Ramanujam N. Madonna MC, et al. Among authors: alvarez jv. Mol Cancer Res. 2019 Jul;17(7):1545-1555. doi: 10.1158/1541-7786.MCR-18-0618. Epub 2019 Mar 22. Mol Cancer Res. 2019. PMID: 30902832 Free PMC article.

3

NRF2 activation promotes the recurrence of dormant tumour cells through regulation of redox and nucleotide metabolism.

Fox DB, Garcia NMG, McKinney BJ, Lupo R, Noteware LC, Newcomb R, Liu J, Locasale JW, Hirschey MD, Alvarez JV. Fox DB, et al. Among authors: alvarez jv. Nat Metab. 2020 Apr;2(4):318-334. doi: 10.1038/s42255-020-0191-z. Epub 2020 Apr 20. Nat Metab. 2020. PMID: 32691018 Free PMC article.

4

Adaptation and selection shape clonal evolution of tumors during residual disease and recurrence.

Walens A, Lin J, Damrauer JS, McKinney B, Lupo R, Newcomb R, Fox DB, Mabe NW, Gresham J, Sheng Z, Sibley AB, De Buysscher T, Kelkar H, Mieczkowski PA, Owzar K, Alvarez JV. Walens A, et al. Among authors: alvarez jv. Nat Commun. 2020 Oct 6;11(1):5017. doi: 10.1038/s41467-020-18730-z. Nat Commun. 2020. PMID: 33024122 Free PMC article.

5

Context-dependent effects of whole-genome duplication during mammary tumor recurrence.

Newcomb R, Dean E, McKinney BJ, Alvarez JV. Newcomb R, et al. Among authors: alvarez jv. Sci Rep. 2021 Jul 22;11(1):14932. doi: 10.1038/s41598-021-94332-z. Sci Rep. 2021. PMID: 34294755 Free PMC article.

6

APOBEC Mutagenesis Inhibits Breast Cancer Growth through Induction of T cell-Mediated Antitumor Immune Responses.

DiMarco AV, Qin X, McKinney BJ, Garcia NMG, Van Alsten SC, Mendes EA, Force J, Hanks BA, Troester MA, Owzar K, Xie J, Alvarez JV. DiMarco AV, et al. Among authors: alvarez jv. Cancer Immunol Res. 2022 Jan;10(1):70-86. doi: 10.1158/2326-6066.CIR-21-0146. Epub 2021 Nov 18. Cancer Immunol Res. 2022. PMID: 34795033 Free PMC article.

7

APOBEC3 activity promotes the survival and evolution of drug-tolerant persister cells during acquired resistance to EGFR inhibitors in lung cancer.

Garcia NMG, Becerra JN, McKinney BJ, DiMarco AV, Wu F, Fitzgibbon M, Alvarez JV. Garcia NMG, et al. Among authors: alvarez jv. bioRxiv [Preprint]. 2024 Nov 20:2023.07.02.547443. doi: 10.1101/2023.07.02.547443. bioRxiv. 2024. PMID: 37461590 Free PMC article. Preprint.

8

Optical imaging reveals chemotherapy-induced metabolic reprogramming of residual disease and recurrence.

Sunassee ED, Deutsch RJ, D'Agostino VW, Castellano-Escuder P, Siebeneck EA, Ilkayeva O, Crouch BT, Madonna MC, Everitt J, Alvarez JV, Palmer GM, Hirschey MD, Ramanujam N. Sunassee ED, et al. Among authors: alvarez jv. Sci Adv. 2024 Apr 5;10(14):eadj7540. doi: 10.1126/sciadv.adj7540. Epub 2024 Apr 5. Sci Adv. 2024. PMID: 38579004 Free PMC article.

9

CCL5 promotes breast cancer recurrence through macrophage recruitment in residual tumors.

Walens A, DiMarco AV, Lupo R, Kroger BR, Damrauer JS, Alvarez JV. Walens A, et al. Among authors: alvarez jv. Elife. 2019 Apr 16;8:e43653. doi: 10.7554/eLife.43653. Elife. 2019. PMID: 30990165 Free PMC article.

10

G9a Promotes Breast Cancer Recurrence through Repression of a Pro-inflammatory Program.

Mabe NW, Garcia NMG, Wolery SE, Newcomb R, Meingasner RC, Vilona BA, Lupo R, Lin CC, Chi JT, Alvarez JV. Mabe NW, et al. Among authors: alvarez jv. Cell Rep. 2020 Nov 3;33(5):108341. doi: 10.1016/j.celrep.2020.108341. Cell Rep. 2020. PMID: 33147463 Free PMC article.

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