Yu W - Search Results

1

GD2-targeting CAR-T cells enhanced by transgenic IL-15 expression are an effective and clinically feasible therapy for glioblastoma.

Gargett T, Ebert LM, Truong NTH, Kollis PM, Sedivakova K, Yu W, Yeo ECF, Wittwer NL, Gliddon BL, Tea MN, Ormsby R, Poonnoose S, Nowicki J, Vittorio O, Ziegler DS, Pitson SM, Brown MP. Gargett T, et al. Among authors: yu w. J Immunother Cancer. 2022 Sep;10(9):e005187. doi: 10.1136/jitc-2022-005187. J Immunother Cancer. 2022. PMID: 36167468 Free PMC article.

2

Induction of antigen-positive cell death by the expression of perforin, but not DTa, from a DNA vaccine enhances the immune response.

Gargett T, Grubor-Bauk B, Garrod TJ, Yu W, Miller D, Major L, Wesselingh S, Suhrbier A, Gowans EJ. Gargett T, et al. Among authors: yu w. Immunol Cell Biol. 2014 Apr;92(4):359-67. doi: 10.1038/icb.2013.93. Epub 2013 Dec 10. Immunol Cell Biol. 2014. PMID: 24323081

3

DNA vaccines encoding membrane-bound or secreted forms of heat shock protein 70 exhibit improved potency.

Garrod TJ, Grubor-Bauk B, Gargett T, Li Y, Miller DS, Yu W, Major L, Burrell CJ, Wesselingh S, Suhrbier A, Gowans EJ. Garrod TJ, et al. Among authors: yu w. Eur J Immunol. 2014 Jul;44(7):1992-2002. doi: 10.1002/eji.201343983. Epub 2014 May 11. Eur J Immunol. 2014. PMID: 24723366 Free article.

4

A novel challenge model to evaluate the efficacy of hepatitis C virus vaccines in mice.

Yu W, Grubor-Bauk B, Gargett T, Garrod T, Gowans EJ. Yu W, et al. Vaccine. 2014 Jun 5;32(27):3409-16. doi: 10.1016/j.vaccine.2014.04.014. Epub 2014 Apr 16. Vaccine. 2014. PMID: 24742491

5

Loss of long term protection with the inclusion of HIV pol to a DNA vaccine encoding gag.

Garrod TJ, Gargett T, Yu W, Major L, Burrell CJ, Wesselingh S, Suhrbier A, Grubor-Bauk B, Gowans EJ. Garrod TJ, et al. Among authors: yu w. Virus Res. 2014 Nov 4;192:25-33. doi: 10.1016/j.virusres.2014.08.008. Epub 2014 Aug 23. Virus Res. 2014. PMID: 25152448

6

GD2-specific CAR T Cells Undergo Potent Activation and Deletion Following Antigen Encounter but can be Protected From Activation-induced Cell Death by PD-1 Blockade.

Gargett T, Yu W, Dotti G, Yvon ES, Christo SN, Hayball JD, Lewis ID, Brenner MK, Brown MP. Gargett T, et al. Among authors: yu w. Mol Ther. 2016 Jun;24(6):1135-1149. doi: 10.1038/mt.2016.63. Epub 2016 Mar 29. Mol Ther. 2016. PMID: 27019998 Free PMC article. Clinical Trial.

7

Comment on "KB004, a first in class monoclonal antibody targeting the receptor tyrosine kinase EphA3, in patients with advanced hematologic malignancies: Results from a phase 1 study".

Hughes A, Clarson J, Gargett T, Yu W, Brown MP, Lopez AF, Hughes TP, Yong AS. Hughes A, et al. Among authors: yu w. Leuk Res. 2017 Apr;55:55-57. doi: 10.1016/j.leukres.2017.01.009. Epub 2017 Jan 9. Leuk Res. 2017. PMID: 28129558 No abstract available.

8

Logic-gated approaches to extend the utility of chimeric antigen receptor T-cell technology.

Ebert LM, Yu W, Gargett T, Brown MP. Ebert LM, et al. Among authors: yu w. Biochem Soc Trans. 2018 Apr 17;46(2):391-401. doi: 10.1042/BST20170178. Epub 2018 Mar 14. Biochem Soc Trans. 2018. PMID: 29540509 Review.

9

Optimization of manufacturing conditions for chimeric antigen receptor T cells to favor cells with a central memory phenotype.

Gargett T, Truong N, Ebert LM, Yu W, Brown MP. Gargett T, et al. Among authors: yu w. Cytotherapy. 2019 Jun;21(6):593-602. doi: 10.1016/j.jcyt.2019.03.003. Epub 2019 Apr 8. Cytotherapy. 2019. PMID: 30975603

10

Endothelial, pericyte and tumor cell expression in glioblastoma identifies fibroblast activation protein (FAP) as an excellent target for immunotherapy.

Ebert LM, Yu W, Gargett T, Toubia J, Kollis PM, Tea MN, Ebert BW, Bardy C, van den Hurk M, Bonder CS, Manavis J, Ensbey KS, Oksdath Mansilla M, Scheer KG, Perrin SL, Ormsby RJ, Poonnoose S, Koszyca B, Pitson SM, Day BW, Gomez GA, Brown MP. Ebert LM, et al. Among authors: yu w. Clin Transl Immunology. 2020 Oct 14;9(10):e1191. doi: 10.1002/cti2.1191. eCollection 2020. Clin Transl Immunology. 2020. PMID: 33082953 Free PMC article.

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