Parrella E - Search Results

1

Fasting-mimicking diet cycles reduce neuroinflammation to attenuate cognitive decline in Alzheimer's models.

Rangan P, Lobo F, Parrella E, Rochette N, Morselli M, Stephen TL, Cremonini AL, Tagliafico L, Persia A, Caffa I, Monacelli F, Odetti P, Bonfiglio T, Nencioni A, Pigliautile M, Boccardi V, Mecocci P, Pike CJ, Cohen P, LaDu MJ, Pellegrini M, Xia K, Tran K, Ann B, Chowdhury D, Longo VD. Rangan P, et al. Among authors: parrella e. Cell Rep. 2022 Sep 27;40(13):111417. doi: 10.1016/j.celrep.2022.111417. Cell Rep. 2022. PMID: 36170815 Free PMC article.

2

The chronological life span of Saccharomyces cerevisiae to study mitochondrial dysfunction and disease.

Parrella E, Longo VD. Parrella E, et al. Methods. 2008 Dec;46(4):256-62. doi: 10.1016/j.ymeth.2008.10.004. Epub 2008 Oct 18. Methods. 2008. PMID: 18930829

3

Insulin/IGF-I and related signaling pathways regulate aging in nondividing cells: from yeast to the mammalian brain.

Parrella E, Longo VD. Parrella E, et al. ScientificWorldJournal. 2010 Jan 21;10:161-77. doi: 10.1100/tsw.2010.8. ScientificWorldJournal. 2010. PMID: 20098959 Free PMC article. Review.

4

Reduced levels of IGF-I mediate differential protection of normal and cancer cells in response to fasting and improve chemotherapeutic index.

Lee C, Safdie FM, Raffaghello L, Wei M, Madia F, Parrella E, Hwang D, Cohen P, Bianchi G, Longo VD. Lee C, et al. Among authors: parrella e. Cancer Res. 2010 Feb 15;70(4):1564-72. doi: 10.1158/0008-5472.CAN-09-3228. Epub 2010 Feb 9. Cancer Res. 2010. PMID: 20145127 Free PMC article.

5

Protein restriction cycles reduce IGF-1 and phosphorylated Tau, and improve behavioral performance in an Alzheimer's disease mouse model.

Parrella E, Maxim T, Maialetti F, Zhang L, Wan J, Wei M, Cohen P, Fontana L, Longo VD. Parrella E, et al. Aging Cell. 2013 Apr;12(2):257-68. doi: 10.1111/acel.12049. Epub 2013 Mar 11. Aging Cell. 2013. PMID: 23362919 Free PMC article.

6

CHF5074 (CSP-1103) induces microglia alternative activation in plaque-free Tg2576 mice and primary glial cultures exposed to beta-amyloid.

Porrini V, Lanzillotta A, Branca C, Benarese M, Parrella E, Lorenzini L, Calzà L, Flaibani R, Spano PF, Imbimbo BP, Pizzi M. Porrini V, et al. Among authors: parrella e. Neuroscience. 2015 Aug 27;302:112-20. doi: 10.1016/j.neuroscience.2014.10.029. Epub 2014 Oct 22. Neuroscience. 2015. PMID: 25450955

7

SIRT1 is essential for normal cognitive function and synaptic plasticity.

Michán S, Li Y, Chou MM, Parrella E, Ge H, Long JM, Allard JS, Lewis K, Miller M, Xu W, Mervis RF, Chen J, Guerin KI, Smith LE, McBurney MW, Sinclair DA, Baudry M, de Cabo R, Longo VD. Michán S, et al. Among authors: parrella e. J Neurosci. 2010 Jul 21;30(29):9695-707. doi: 10.1523/JNEUROSCI.0027-10.2010. J Neurosci. 2010. PMID: 20660252 Free PMC article.

8

Mild Inflammatory Profile without Gliosis in the c-Rel Deficient Mouse Modeling a Late-Onset Parkinsonism.

Porrini V, Mota M, Parrella E, Bellucci A, Benarese M, Faggi L, Tonin P, Spano PF, Pizzi M. Porrini V, et al. Among authors: parrella e. Front Aging Neurosci. 2017 Jul 19;9:229. doi: 10.3389/fnagi.2017.00229. eCollection 2017. Front Aging Neurosci. 2017. PMID: 28769786 Free PMC article.

9

Beneficial and Sexually Dimorphic Response to Combined HDAC Inhibitor Valproate and AMPK/SIRT1 Pathway Activator Resveratrol in the Treatment of ALS Mice.

Bankole O, Scambi I, Parrella E, Muccilli M, Bonafede R, Turano E, Pizzi M, Mariotti R. Bankole O, et al. Among authors: parrella e. Int J Mol Sci. 2022 Jan 19;23(3):1047. doi: 10.3390/ijms23031047. Int J Mol Sci. 2022. PMID: 35162978 Free PMC article.

10

Acetylation state of RelA modulated by epigenetic drugs prolongs survival and induces a neuroprotective effect on ALS murine model.

Schiaffino L, Bonafede R, Scambi I, Parrella E, Pizzi M, Mariotti R. Schiaffino L, et al. Among authors: parrella e. Sci Rep. 2018 Aug 27;8(1):12875. doi: 10.1038/s41598-018-30659-4. Sci Rep. 2018. PMID: 30150770 Free PMC article.

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