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Cannabinoid receptor type 2 is upregulated in synovium following joint injury and mediates anti-inflammatory effects in synovial fibroblasts and macrophages.
Rzeczycki P, Rasner C, Lammlin L, Junginger L, Goldman S, Bergman R, Redding S, Knights AJ, Elliott M, Maerz T. Rzeczycki P, et al. Among authors: lammlin l. Osteoarthritis Cartilage. 2021 Dec;29(12):1720-1731. doi: 10.1016/j.joca.2021.09.003. Epub 2021 Sep 17. Osteoarthritis Cartilage. 2021. PMID: 34537380 Free PMC article.