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CYP2D6 and CYP2C8 pharmacogenetics and pharmacological interactions to predict imatinib plasmatic exposure in GIST patients.
Dalle Fratte C, Gagno S, Roncato R, Polesel J, Zanchetta M, Buzzo M, Posocco B, De Mattia E, Borsatti R, Puglisi F, Foltran L, Guardascione M, Buonadonna A, Cecchin E, Toffoli G. Dalle Fratte C, et al. Among authors: posocco b. Br J Clin Pharmacol. 2023 Mar;89(3):1089-1098. doi: 10.1111/bcp.15551. Epub 2022 Oct 19. Br J Clin Pharmacol. 2023. PMID: 36178950 Free article.
Development and validation of a high-performance liquid chromatography-tandem mass spectrometry method for the simultaneous determination of irinotecan and its main metabolites in human plasma and its application in a clinical pharmacokinetic study.
Marangon E, Posocco B, Mazzega E, Toffoli G. Marangon E, et al. Among authors: posocco b. PLoS One. 2015 Feb 17;10(2):e0118194. doi: 10.1371/journal.pone.0118194. eCollection 2015. PLoS One. 2015. PMID: 25689738 Free PMC article.
Matrix-assisted laser desorption/ionization, nanostructure-assisted laser desorption/ionization and carbon nanohorns in the detection of antineoplastic drugs. 1. The cases of irinotecan, sunitinib and 6-alpha-hydroxy paclitaxel.
Traldi P, Calandra E, Crotti S, Agostini M, Nitti D, Roverso M, Toffoli G, Marangon E, Posocco B. Traldi P, et al. Among authors: posocco b. Eur J Mass Spectrom (Chichester). 2014;20(6):445-59. doi: 10.1255/ejms.1302. Eur J Mass Spectrom (Chichester). 2014. PMID: 25905869
Cross-validation of a mass spectrometric-based method for the therapeutic drug monitoring of irinotecan: implementation of matrix-assisted laser desorption/ionization mass spectrometry in pharmacokinetic measurements.
Calandra E, Posocco B, Crotti S, Marangon E, Giodini L, Nitti D, Toffoli G, Traldi P, Agostini M. Calandra E, et al. Among authors: posocco b. Anal Bioanal Chem. 2016 Jul;408(19):5369-77. doi: 10.1007/s00216-016-9634-5. Epub 2016 May 27. Anal Bioanal Chem. 2016. PMID: 27235158 Clinical Trial.
Nanocarriers in cancer clinical practice: a pharmacokinetic issue.
Giodini L, Re FL, Campagnol D, Marangon E, Posocco B, Dreussi E, Toffoli G. Giodini L, et al. Among authors: posocco b. Nanomedicine. 2017 Feb;13(2):583-599. doi: 10.1016/j.nano.2016.07.012. Epub 2016 Aug 9. Nanomedicine. 2017. PMID: 27520727 Review.
41 results