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A novel automated morphological analysis of Iba1+ microglia using a deep learning assisted model.
Stetzik L, Mercado G, Smith L, George S, Quansah E, Luda K, Schulz E, Meyerdirk L, Lindquist A, Bergsma A, Jones RG, Brundin L, Henderson MX, Pospisilik JA, Brundin P. Stetzik L, et al. Among authors: schulz e. Front Cell Neurosci. 2022 Sep 15;16:944875. doi: 10.3389/fncel.2022.944875. eCollection 2022. Front Cell Neurosci. 2022. PMID: 36187297 Free PMC article.
Mitochondrial pyruvate carrier regulates autophagy, inflammation, and neurodegeneration in experimental models of Parkinson's disease.
Ghosh A, Tyson T, George S, Hildebrandt EN, Steiner JA, Madaj Z, Schulz E, Machiela E, McDonald WG, Escobar Galvis ML, Kordower JH, Van Raamsdonk JM, Colca JR, Brundin P. Ghosh A, et al. Among authors: schulz e. Sci Transl Med. 2016 Dec 7;8(368):368ra174. doi: 10.1126/scitranslmed.aag2210. Sci Transl Med. 2016. PMID: 27928028
Biochemical Profiling of the Brain and Blood Metabolome in a Mouse Model of Prodromal Parkinson's Disease Reveals Distinct Metabolic Profiles.
Graham SF, Rey NL, Yilmaz A, Kumar P, Madaj Z, Maddens M, Bahado-Singh RO, Becker K, Schulz E, Meyerdirk LK, Steiner JA, Ma J, Brundin P. Graham SF, et al. Among authors: schulz e. J Proteome Res. 2018 Jul 6;17(7):2460-2469. doi: 10.1021/acs.jproteome.8b00224. Epub 2018 May 25. J Proteome Res. 2018. PMID: 29762036 Free PMC article.
T Cells Limit Accumulation of Aggregate Pathology Following Intrastriatal Injection of α-Synuclein Fibrils.
George S, Tyson T, Rey NL, Sheridan R, Peelaerts W, Becker K, Schulz E, Meyerdirk L, Burmeister AR, von Linstow CU, Steiner JA, Galvis MLE, Ma J, Pospisilik JA, Labrie V, Brundin L, Brundin P. George S, et al. Among authors: schulz e. J Parkinsons Dis. 2021;11(2):585-603. doi: 10.3233/JPD-202351. J Parkinsons Dis. 2021. PMID: 33579871 Free PMC article.
Inhibiting the mitochondrial pyruvate carrier does not ameliorate synucleinopathy in the absence of inflammation or metabolic deficits.
Peelaerts W, Bergkvist L, George S, Johnson M, Meyerdirk L, Schulz E, Steiner JA, Madaj Z, Ma J, Becker K, Nilsson KPR, Colca JR, Brundin P. Peelaerts W, et al. Among authors: schulz e. Free Neuropathol. 2020;1:1-33. doi: 10.17879/freeneuropathology-2020-3049. Epub 2020 Nov 25. Free Neuropathol. 2020. PMID: 35224554 Free PMC article.
1,090 results