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Page 1
Hydroxymethylation profile of cell-free DNA is a biomarker for early colorectal cancer.
Walker NJ, Rashid M, Yu S, Bignell H, Lumby CK, Livi CM, Howell K, Morley DJ, Morganella S, Barrell D, Caim S, Gosal W, Füllgrabe J, Charlesworth TJ, Vasquez L, Ahdesmäki M, Eizenga J, Prabhat P, Proutski V, Murat-Onana ML, Greenwood CJ, Kirkwood L, Maisuria-Armer M, Li M, Coats E, Winfield V, MacBean L, Stock T, Tomé-Fernandez A, Chan Y, Sheikh N, Golder P, Steward M, Ost TWB, Stewart D, Vilella A, Noursalehi M, Paten B, Lucarelli D, Mason J, Ridge G, Mellad J, Shirodkar S, Balasubaramanian S, Holbrook JD. Walker NJ, et al. Among authors: mellad j. Sci Rep. 2022 Oct 4;12(1):16566. doi: 10.1038/s41598-022-20975-1. Sci Rep. 2022. PMID: 36195648 Free PMC article.
Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.
Zhang Q, Bethmann C, Worth NF, Davies JD, Wasner C, Feuer A, Ragnauth CD, Yi Q, Mellad JA, Warren DT, Wheeler MA, Ellis JA, Skepper JN, Vorgerd M, Schlotter-Weigel B, Weissberg PL, Roberts RG, Wehnert M, Shanahan CM. Zhang Q, et al. Hum Mol Genet. 2007 Dec 1;16(23):2816-33. doi: 10.1093/hmg/ddm238. Epub 2007 Aug 29. Hum Mol Genet. 2007. PMID: 17761684
Nesprins LINC the nucleus and cytoskeleton.
Mellad JA, Warren DT, Shanahan CM. Mellad JA, et al. Curr Opin Cell Biol. 2011 Feb;23(1):47-54. doi: 10.1016/j.ceb.2010.11.006. Epub 2010 Dec 20. Curr Opin Cell Biol. 2011. PMID: 21177090 Review.
Mammalian microtubule P-body dynamics are mediated by nesprin-1.
Rajgor D, Mellad JA, Soong D, Rattner JB, Fritzler MJ, Shanahan CM. Rajgor D, et al. Among authors: mellad ja. J Cell Biol. 2014 May 26;205(4):457-75. doi: 10.1083/jcb.201306076. J Cell Biol. 2014. PMID: 24862572 Free PMC article.
Simultaneous sequencing of genetic and epigenetic bases in DNA.
Füllgrabe J, Gosal WS, Creed P, Liu S, Lumby CK, Morley DJ, Ost TWB, Vilella AJ, Yu S, Bignell H, Burns P, Charlesworth T, Fu B, Fordham H, Harding NJ, Gandelman O, Golder P, Hodson C, Li M, Lila M, Liu Y, Mason J, Mellad J, Monahan JM, Nentwich O, Palmer A, Steward M, Taipale M, Vandomme A, San-Bento RS, Singhal A, Vivian J, Wójtowicz N, Williams N, Walker NJ, Wong NCH, Yalloway GN, Holbrook JD, Balasubramanian S. Füllgrabe J, et al. Among authors: mellad j. Nat Biotechnol. 2023 Oct;41(10):1457-1464. doi: 10.1038/s41587-022-01652-0. Epub 2023 Feb 6. Nat Biotechnol. 2023. PMID: 36747096 Free PMC article.
Publisher Correction: Voices of biotech leaders.
Bosley K, Casebourn C, Chan P, Chen J, Chen M, Church G, Cumbers J, de Wouters T, Dewey-Hagborg H, Duportet X, Ene-Obong A, Elizondo A, Farrar J, Gates B, Gatto F, Giwa S, Godec J, Gold S, LeProust E, Lunshof J, Martucci E, Heath MM, Mellad J, Oudova V, Oxman N, Regev A, Richardson S, Scott CT, Sherkow J, Sibener L, Tarragó T, Terry S, Venter JC, Wang S, Wickramasekara S, Yadi H, Yang L, Zhao B. Bosley K, et al. Among authors: mellad j. Nat Biotechnol. 2021 Aug;39(8):1017. doi: 10.1038/s41587-021-01000-8. Nat Biotechnol. 2021. PMID: 34290438 No abstract available.
Voices of biotech leaders.
Bosley K, Casebourn C, Chan P, Chen J, Chen M, Church G, Cumbers J, de Wouters T, Dewey-Hagborg H, Duportet X, Ene-Obong A, Elizondo A, Farrar J, Gates B, Gatto F, Giwa S, Godec J, Gold S, LeProust E, Lunshof J, Martucci E, Heath MM, Mellad J, Oudova V, Oxman N, Regev A, Richardson S, Scott CT, Sherkow J, Sibener L, Tarragó T, Terry S, Venter JC, Wang S, Wickramasekara S, Yadi H, Yang L, Zhao B. Bosley K, et al. Among authors: mellad j. Nat Biotechnol. 2021 Jun;39(6):654-660. doi: 10.1038/s41587-021-00941-4. Nat Biotechnol. 2021. PMID: 34113035 No abstract available.
TGF-β signaling mediates endothelial-to-mesenchymal transition (EndMT) during vein graft remodeling.
Cooley BC, Nevado J, Mellad J, Yang D, St Hilaire C, Negro A, Fang F, Chen G, San H, Walts AD, Schwartzbeck RL, Taylor B, Lanzer JD, Wragg A, Elagha A, Beltran LE, Berry C, Feil R, Virmani R, Ladich E, Kovacic JC, Boehm M. Cooley BC, et al. Among authors: mellad j. Sci Transl Med. 2014 Mar 12;6(227):227ra34. doi: 10.1126/scitranslmed.3006927. Sci Transl Med. 2014. PMID: 24622514 Free PMC article.
14 results