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Radiation with STAT3 Blockade Triggers Dendritic Cell-T cell Interactions in the Glioma Microenvironment and Therapeutic Efficacy.
Ott M, Kassab C, Marisetty A, Hashimoto Y, Wei J, Zamler D, Leu JS, Tomaszowski KH, Sabbagh A, Fang D, Gupta P, Priebe W, Zielinski RJ, Burks JK, Long JP, Kong LY, Fuller GN, DeGroot J, Sulman EP, Heimberger AB. Ott M, et al. Among authors: burks jk. Clin Cancer Res. 2020 Sep 15;26(18):4983-4994. doi: 10.1158/1078-0432.CCR-19-4092. Epub 2020 Jun 30. Clin Cancer Res. 2020. PMID: 32605912 Free PMC article.
Spontaneous tumor regression following COVID-19 vaccination.
Sousa LG, McGrail DJ, Li K, Marques-Piubelli ML, Gonzalez C, Dai H, Ferri-Borgogno S, Godoy M, Burks J, Lin SY, Bell D, Ferrarotto R. Sousa LG, et al. J Immunother Cancer. 2022 Mar;10(3):e004371. doi: 10.1136/jitc-2021-004371. J Immunother Cancer. 2022. PMID: 35241495 Free PMC article.
Central nervous system immune interactome is a function of cancer lineage, tumor microenvironment, and STAT3 expression.
Najem H, Ott M, Kassab C, Rao A, Rao G, Marisetty A, Sonabend AM, Horbinski C, Verhaak R, Shankar A, Krishnan SN, Varn FS, Arrieta VA, Gupta P, Ferguson SD, Huse JT, Fuller GN, Long JP, Winkowski DE, Freiberg BA, James CD, Platanias LC, Lesniak MS, Burks JK, Heimberger AB. Najem H, et al. Among authors: burks jk. JCI Insight. 2022 May 9;7(9):e157612. doi: 10.1172/jci.insight.157612. JCI Insight. 2022. PMID: 35316217 Free PMC article.
Spatial Immunoprofiling of Adenoid Cystic Carcinoma Reveals B7-H4 Is a Therapeutic Target for Aggressive Tumors.
Sousa LG, McGrail DJ, Lazar Neto F, Li K, Marques-Piubelli ML, Ferri-Borgogno S, Dai H, Mitani Y, Spardy Burr N, Cooper ZA, Kinneer K, Cortez MA, Lin SY, Bell D, El Naggar A, Burks J, Ferrarotto R. Sousa LG, et al. Clin Cancer Res. 2023 Aug 15;29(16):3162-3171. doi: 10.1158/1078-0432.CCR-23-0514. Clin Cancer Res. 2023. PMID: 37256648 Free PMC article.
Inflammation induced by tumor-associated nerves promotes resistance to anti-PD-1 therapy in cancer patients and is targetable by interleukin-6 blockade.
Baruch EN, Nagarajan P, Gleber-Netto FO, Rao X, Xie T, Akhter S, Adewale A, Shajedul I, Mattson BJ, Ferrarotto R, Wong MK, Davies MA, Jindal S, Basu S, Harwood C, Leigh I, Ajami N, Futreal A, Castillo M, Gunaratne P, Goepfert RP, Khushalani N, Wang J, Watowich S, Calin GA, Migden MR, Vermeer P, D'Silva N, Yaniv D, Burks JK, Gomez J, Dougherty PM, Tsai KY, Allison JP, Sharma P, Wargo J, Myers JN, Gross ND, Amit M. Baruch EN, et al. Among authors: burks jk. Res Sq [Preprint]. 2023 Jul 18:rs.3.rs-3161761. doi: 10.21203/rs.3.rs-3161761/v1. Res Sq. 2023. PMID: 37503252 Free PMC article. Preprint.
Mutant p53 gains oncogenic functions through a chromosomal instability-induced cytosolic DNA response.
Zhao M, Wang T, Gleber-Netto FO, Chen Z, McGrail DJ, Gomez JA, Ju W, Gadhikar MA, Ma W, Shen L, Wang Q, Tang X, Pathak S, Raso MG, Burks JK, Lin SY, Wang J, Multani AS, Pickering CR, Chen J, Myers JN, Zhou G. Zhao M, et al. Among authors: burks jk. Nat Commun. 2024 Jan 2;15(1):180. doi: 10.1038/s41467-023-44239-2. Nat Commun. 2024. PMID: 38167338 Free PMC article.
Neural landscape is associated with functional outcomes in irradiated patients with oropharyngeal squamous cell carcinoma.
Islam S, Gleber-Netto FO, Mulcahy CF, Glaun MDE, Srivastava S, Hunt PJ, Williams MD, Barbon CE, Spiotto M, Zhao W, Adebayo A, Akhter S, Xie T, Debnath KC, Sathishkumar HN, Myers B, Lothumalla S, Yaman I, Burks JK, Gomez J, Rao X, Wang J, Woodman K, Mansour J, Arenkiel B, Osman KL, Haxton C, Lever TE, Hutcheson KA, Amit M. Islam S, et al. Among authors: burks jk. Sci Transl Med. 2024 Jul 31;16(758):eabq5585. doi: 10.1126/scitranslmed.abq5585. Epub 2024 Jul 31. Sci Transl Med. 2024. PMID: 39083586
Glioblastoma stem cell-derived exosomes induce M2 macrophages and PD-L1 expression on human monocytes.
Gabrusiewicz K, Li X, Wei J, Hashimoto Y, Marisetty AL, Ott M, Wang F, Hawke D, Yu J, Healy LM, Hossain A, Akers JC, Maiti SN, Yamashita S, Shimizu Y, Dunner K, Zal MA, Burks JK, Gumin J, Nwajei F, Rezavanian A, Zhou S, Rao G, Sawaya R, Fuller GN, Huse JT, Antel JP, Li S, Cooper L, Sulman EP, Chen C, Geula C, Kalluri R, Zal T, Heimberger AB. Gabrusiewicz K, et al. Among authors: burks jk. Oncoimmunology. 2018 Jan 16;7(4):e1412909. doi: 10.1080/2162402X.2017.1412909. eCollection 2018. Oncoimmunology. 2018. PMID: 29632728 Free PMC article.
97 results