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Co-targeting of HDAC, PI3K, and Bcl-2 results in metabolic and transcriptional reprogramming and decreased mitochondrial function in acute myeloid leukemia.
Hege Hurrish K, Qiao X, Li X, Su Y, Carter J, Ma J, Kalpage HA, Hüttemann M, Edwards H, Wang G, Kim S, Dombkowski A, Bao X, Li J, Taub JW, Ge Y. Hege Hurrish K, et al. Among authors: kalpage ha. Biochem Pharmacol. 2022 Nov;205:115283. doi: 10.1016/j.bcp.2022.115283. Epub 2022 Oct 5. Biochem Pharmacol. 2022. PMID: 36208684 Free PMC article.
Cotargeting of Mitochondrial Complex I and Bcl-2 Shows Antileukemic Activity against Acute Myeloid Leukemia Cells Reliant on Oxidative Phosphorylation.
Liu F, Kalpage HA, Wang D, Edwards H, Hüttemann M, Ma J, Su Y, Carter J, Li X, Polin L, Kushner J, Dzinic SH, White K, Wang G, Taub JW, Ge Y. Liu F, et al. Among authors: kalpage ha. Cancers (Basel). 2020 Aug 24;12(9):2400. doi: 10.3390/cancers12092400. Cancers (Basel). 2020. PMID: 32847115 Free PMC article.
Regulation of Respiration and Apoptosis by Cytochrome c Threonine 58 Phosphorylation.
Wan J, Kalpage HA, Vaishnav A, Liu J, Lee I, Mahapatra G, Turner AA, Zurek MP, Ji Q, Moraes CT, Recanati MA, Grossman LI, Salomon AR, Edwards BFP, Hüttemann M. Wan J, et al. Among authors: kalpage ha. Sci Rep. 2019 Nov 1;9(1):15815. doi: 10.1038/s41598-019-52101-z. Sci Rep. 2019. PMID: 31676852 Free PMC article.
18 results