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A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo.
Kofink C, Trainor N, Mair B, Wöhrle S, Wurm M, Mischerikow N, Roy MJ, Bader G, Greb P, Garavel G, Diers E, McLennan R, Whitworth C, Vetma V, Rumpel K, Scharnweber M, Fuchs JE, Gerstberger T, Cui Y, Gremel G, Chetta P, Hopf S, Budano N, Rinnenthal J, Gmaschitz G, Mayer M, Koegl M, Ciulli A, Weinstabl H, Farnaby W. Kofink C, et al. Among authors: hopf s. Nat Commun. 2022 Oct 10;13(1):5969. doi: 10.1038/s41467-022-33430-6. Nat Commun. 2022. PMID: 36216795 Free PMC article.
Riboswitch-controlled IL-12 gene therapy reduces hepatocellular cancer in mice.
Düchs MJ, Kratzer RF, Vieyra-Garcia P, Strobel B, Schönberger T, Groß P, Aljayyoussi G, Gupta A, Lang I, Klein H, Morilla SM, Hopf S, Park J, Kreuz S, Klugmann M, Igney FH. Düchs MJ, et al. Among authors: hopf s. Front Immunol. 2024 Mar 15;15:1360063. doi: 10.3389/fimmu.2024.1360063. eCollection 2024. Front Immunol. 2024. PMID: 38558809 Free PMC article.
Ageism: An Old Concept From New Perspectives.
Ayalon L, Mannheim I, Hopf S, Casal-Sanchez L, Kydd A. Ayalon L, et al. Among authors: hopf s. J Appl Gerontol. 2023 Jun;42(6):1176-1178. doi: 10.1177/07334648231165352. J Appl Gerontol. 2023. PMID: 37204258 No abstract available.
67 results