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2,104 results

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Page 1
Integrin alpha9 emerges as a key therapeutic target to reduce metastasis in rhabdomyosarcoma and neuroblastoma.
Navarro N, Molist C, Sansa-Girona J, Zarzosa P, Gallo-Oller G, Pons G, Magdaleno A, Guillén G, Hladun R, Garrido M, Segura MF, Hontecillas-Prieto L, de Álava E, Ponsati B, Fernández-Carneado J, Almazán-Moga A, Vallès-Miret M, Farrera-Sinfreu J, de Toledo JS, Moreno L, Gallego S, Roma J. Navarro N, et al. Among authors: moreno l. Cell Mol Life Sci. 2022 Oct 11;79(11):546. doi: 10.1007/s00018-022-04557-y. Cell Mol Life Sci. 2022. PMID: 36221013 Free PMC article.
CN133, a Novel Brain-Penetrating Histone Deacetylase Inhibitor, Hampers Tumor Growth in Patient-Derived Pediatric Posterior Fossa Ependymoma Models.
Antonelli R, Jiménez C, Riley M, Servidei T, Riccardi R, Soriano A, Roma J, Martínez-Saez E, Martini M, Ruggiero A, Moreno L, Sánchez de Toledo J, Gallego S, Bové J, Hooker JM, Segura MF. Antonelli R, et al. Among authors: moreno l. Cancers (Basel). 2020 Jul 16;12(7):1922. doi: 10.3390/cancers12071922. Cancers (Basel). 2020. PMID: 32708733 Free PMC article.
The antitumour drug ABTL0812 impairs neuroblastoma growth through endoplasmic reticulum stress-mediated autophagy and apoptosis.
París-Coderch L, Soriano A, Jiménez C, Erazo T, Muñoz-Guardiola P, Masanas M, Antonelli R, Boloix A, Alfón J, Pérez-Montoyo H, Yeste-Velasco M, Domènech C, Roma J, Sánchez de Toledo J, Moreno L, Lizcano JM, Gallego S, Segura MF. París-Coderch L, et al. Among authors: moreno l. Cell Death Dis. 2020 Sep 17;11(9):773. doi: 10.1038/s41419-020-02986-w. Cell Death Dis. 2020. PMID: 32943619 Free PMC article.
Neuronal Differentiation-Related Epigenetic Regulator ZRF1 Has Independent Prognostic Value in Neuroblastoma but Is Functionally Dispensable In Vitro.
Jiménez C, Antonelli R, Masanas M, Soriano A, Devis-Jauregui L, Camacho J, Magdaleno A, Guillén G, Hladun R, Jubierre L, Roma J, Llobet-Navas D, Sánchez de Toledo J, Moreno L, Gallego S, Segura MF. Jiménez C, et al. Among authors: moreno l. Cancers (Basel). 2021 Sep 28;13(19):4845. doi: 10.3390/cancers13194845. Cancers (Basel). 2021. PMID: 34638328 Free PMC article.
The oral KIF11 inhibitor 4SC-205 exhibits antitumor activity and potentiates standard and targeted therapies in primary and metastatic neuroblastoma models.
Masanas M, Masiá N, Suárez-Cabrera L, Olivan M, Soriano A, Majem B, Devis-Jauregui L, Burgos-Panadero R, Jiménez C, Rodriguez-Sodupe P, Boloix A, Toledano I, Guillén G, Navarro A, Llobet-Navas D, Villanueva A, Sánchez de Toledo J, Roma J, Noguera R, Moreno L, Krauss R, Gallego S, Santamaria A, Segura MF. Masanas M, et al. Among authors: moreno l. Clin Transl Med. 2021 Oct;11(10):e533. doi: 10.1002/ctm2.533. Clin Transl Med. 2021. PMID: 34709738 Free PMC article. No abstract available.
Methodological advances in the discovery of novel neuroblastoma therapeutics.
Segura MF, Soriano A, Roma J, Piskareva O, Jiménez C, Boloix A, Fletcher JI, Haber M, Gray JC, Cerdá-Alberich L, Martínez de Las Heras B, Cañete A, Gallego S, Moreno L. Segura MF, et al. Among authors: moreno l. Expert Opin Drug Discov. 2022 Feb;17(2):167-179. doi: 10.1080/17460441.2022.2002297. Epub 2021 Nov 22. Expert Opin Drug Discov. 2022. PMID: 34807782 Review.
Dickkopf-1 Inhibition Reactivates Wnt/β-Catenin Signaling in Rhabdomyosarcoma, Induces Myogenic Markers In Vitro and Impairs Tumor Cell Survival In Vivo.
Giralt I, Gallo-Oller G, Navarro N, Zarzosa P, Pons G, Magdaleno A, Segura MF, Sábado C, Hladun R, Arango D, Sánchez de Toledo J, Moreno L, Gallego S, Roma J. Giralt I, et al. Among authors: moreno l. Int J Mol Sci. 2021 Nov 29;22(23):12921. doi: 10.3390/ijms222312921. Int J Mol Sci. 2021. PMID: 34884726 Free PMC article.
Structural disruption of BAF chromatin remodeller impairs neuroblastoma metastasis by reverting an invasiveness epigenomic program.
Jiménez C, Antonelli R, Nadal-Ribelles M, Devis-Jauregui L, Latorre P, Solé C, Masanas M, Molero-Valenzuela A, Soriano A, Sánchez de Toledo J, Llobet-Navas D, Roma J, Posas F, de Nadal E, Gallego S, Moreno L, Segura MF. Jiménez C, et al. Among authors: moreno l. Mol Cancer. 2022 Sep 3;21(1):175. doi: 10.1186/s12943-022-01643-4. Mol Cancer. 2022. PMID: 36057593 Free PMC article.
Advances in the approaches used to repurpose drugs for neuroblastoma.
Miera-Maluenda M, Pérez-Torres M, Mañas A, Rubio-San-Simón A, Butjosa-Espín M, Ruiz-Duran P, Seoane JA, Moreno L, Segura MF. Miera-Maluenda M, et al. Among authors: moreno l. Expert Opin Drug Discov. 2024 Nov;19(11):1309-1319. doi: 10.1080/17460441.2024.2402413. Epub 2024 Sep 11. Expert Opin Drug Discov. 2024. PMID: 39258785 Review.
2,104 results