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Page 1
Safety, Outcomes, and T-Cell Characteristics in Patients with Relapsed or Refractory MDS or CMML Treated with Atezolizumab in Combination with Guadecitabine.
O'Connell CL, Baer MR, Ørskov AD, Saini SK, Duong VH, Kropf P, Hansen JW, Tsao-Wei D, Jang HS, Emadi A, Holmberg-Thyden S, Cowland J, Brinker BT, Horwood K, Burgos R, Hostetter G, Youngblood BA, Hadrup SR, Issa JP, Jones P, Baylin SB, Siddiqi I, Grønbaek K. O'Connell CL, et al. Among authors: orskov ad. Clin Cancer Res. 2022 Dec 15;28(24):5306-5316. doi: 10.1158/1078-0432.CCR-22-1810. Clin Cancer Res. 2022. PMID: 36222848 Free PMC article. Clinical Trial.
Immune Mechanisms in Myelodysplastic Syndrome.
Glenthøj A, Ørskov AD, Hansen JW, Hadrup SR, O'Connell C, Grønbæk K. Glenthøj A, et al. Among authors: orskov ad. Int J Mol Sci. 2016 Jun 15;17(6):944. doi: 10.3390/ijms17060944. Int J Mol Sci. 2016. PMID: 27314337 Free PMC article. Review.
Vitamin C increases viral mimicry induced by 5-aza-2'-deoxycytidine.
Liu M, Ohtani H, Zhou W, Ørskov AD, Charlet J, Zhang YW, Shen H, Baylin SB, Liang G, Grønbæk K, Jones PA. Liu M, et al. Among authors: orskov ad. Proc Natl Acad Sci U S A. 2016 Sep 13;113(37):10238-44. doi: 10.1073/pnas.1612262113. Epub 2016 Aug 29. Proc Natl Acad Sci U S A. 2016. PMID: 27573823 Free PMC article.
Vitamin C - A new player in regulation of the cancer epigenome.
Gillberg L, Ørskov AD, Liu M, Harsløf LBS, Jones PA, Grønbæk K. Gillberg L, et al. Among authors: orskov ad. Semin Cancer Biol. 2018 Aug;51:59-67. doi: 10.1016/j.semcancer.2017.11.001. Epub 2017 Nov 2. Semin Cancer Biol. 2018. PMID: 29102482 Review.
Oral vitamin C supplementation to patients with myeloid cancer on azacitidine treatment: Normalization of plasma vitamin C induces epigenetic changes.
Gillberg L, Ørskov AD, Nasif A, Ohtani H, Madaj Z, Hansen JW, Rapin N, Mogensen JB, Liu M, Dufva IH, Lykkesfeldt J, Hajkova P, Jones PA, Grønbæk K. Gillberg L, et al. Among authors: orskov ad. Clin Epigenetics. 2019 Oct 17;11(1):143. doi: 10.1186/s13148-019-0739-5. Clin Epigenetics. 2019. PMID: 31623675 Free PMC article. Clinical Trial.
Activation of a Subset of Evolutionarily Young Transposable Elements and Innate Immunity Are Linked to Clinical Responses to 5-Azacytidine.
Ohtani H, Ørskov AD, Helbo AS, Gillberg L, Liu M, Zhou W, Ungerstedt J, Hellström-Lindberg E, Sun W, Liang G, Jones PA, Grønbæk K. Ohtani H, et al. Among authors: orskov ad. Cancer Res. 2020 Jun 15;80(12):2441-2450. doi: 10.1158/0008-5472.CAN-19-1696. Epub 2020 Apr 3. Cancer Res. 2020. PMID: 32245794 Free PMC article.
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