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Page 1
Safety, Outcomes, and T-Cell Characteristics in Patients with Relapsed or Refractory MDS or CMML Treated with Atezolizumab in Combination with Guadecitabine.
O'Connell CL, Baer MR, Ørskov AD, Saini SK, Duong VH, Kropf P, Hansen JW, Tsao-Wei D, Jang HS, Emadi A, Holmberg-Thyden S, Cowland J, Brinker BT, Horwood K, Burgos R, Hostetter G, Youngblood BA, Hadrup SR, Issa JP, Jones P, Baylin SB, Siddiqi I, Grønbaek K. O'Connell CL, et al. Among authors: issa jp. Clin Cancer Res. 2022 Dec 15;28(24):5306-5316. doi: 10.1158/1078-0432.CCR-22-1810. Clin Cancer Res. 2022. PMID: 36222848 Free PMC article. Clinical Trial.
A blueprint for an international cancer epigenome consortium. A report from the AACR Cancer Epigenome Task Force.
Beck S, Bernstein BE, Campbell RM, Costello JF, Dhanak D, Ecker JR, Greally JM, Issa JP, Laird PW, Polyak K, Tycko B, Jones PA; AACR Cancer Epigenome Task Force. Beck S, et al. Among authors: issa jp. Cancer Res. 2012 Dec 15;72(24):6319-24. doi: 10.1158/0008-5472.CAN-12-3658. Epub 2012 Nov 27. Cancer Res. 2012. PMID: 23188507 No abstract available.
Transient low doses of DNA-demethylating agents exert durable antitumor effects on hematological and epithelial tumor cells.
Tsai HC, Li H, Van Neste L, Cai Y, Robert C, Rassool FV, Shin JJ, Harbom KM, Beaty R, Pappou E, Harris J, Yen RW, Ahuja N, Brock MV, Stearns V, Feller-Kopman D, Yarmus LB, Lin YC, Welm AL, Issa JP, Minn I, Matsui W, Jang YY, Sharkis SJ, Baylin SB, Zahnow CA. Tsai HC, et al. Among authors: issa jp. Cancer Cell. 2012 Mar 20;21(3):430-46. doi: 10.1016/j.ccr.2011.12.029. Cancer Cell. 2012. PMID: 22439938 Free PMC article.
The Two-Hit Hypothesis Meets Epigenetics.
Issa JP. Issa JP. Cancer Res. 2022 Apr 1;82(7):1167-1169. doi: 10.1158/0008-5472.CAN-22-0405. Cancer Res. 2022. PMID: 35373289 Free PMC article.
Aging-like Spontaneous Epigenetic Silencing Facilitates Wnt Activation, Stemness, and BrafV600E-Induced Tumorigenesis.
Tao Y, Kang B, Petkovich DA, Bhandari YR, In J, Stein-O'Brien G, Kong X, Xie W, Zachos N, Maegawa S, Vaidya H, Brown S, Chiu Yen RW, Shao X, Thakor J, Lu Z, Cai Y, Zhang Y, Mallona I, Peinado MA, Zahnow CA, Ahuja N, Fertig E, Issa JP, Baylin SB, Easwaran H. Tao Y, et al. Among authors: issa jp. Cancer Cell. 2019 Feb 11;35(2):315-328.e6. doi: 10.1016/j.ccell.2019.01.005. Cancer Cell. 2019. PMID: 30753828 Free PMC article.
DNA methylation as a clinical marker in oncology.
Issa JP. Issa JP. J Clin Oncol. 2012 Jul 10;30(20):2566-8. doi: 10.1200/JCO.2012.42.1016. Epub 2012 May 7. J Clin Oncol. 2012. PMID: 22564986 No abstract available.
Cancer prevention: epigenetics steps up to the plate.
Issa JP. Issa JP. Cancer Prev Res (Phila). 2008 Sep;1(4):219-22. doi: 10.1158/1940-6207.CAPR-08-0029. Epub 2008 Mar 19. Cancer Prev Res (Phila). 2008. PMID: 19138962 No abstract available.
Roadmap for investigating epigenome deregulation and environmental origins of cancer.
Herceg Z, Ghantous A, Wild CP, Sklias A, Casati L, Duthie SJ, Fry R, Issa JP, Kellermayer R, Koturbash I, Kondo Y, Lepeule J, Lima SCS, Marsit CJ, Rakyan V, Saffery R, Taylor JA, Teschendorff AE, Ushijima T, Vineis P, Walker CL, Waterland RA, Wiemels J, Ambatipudi S, Degli Esposti D, Hernandez-Vargas H. Herceg Z, et al. Among authors: issa jp. Int J Cancer. 2018 Mar 1;142(5):874-882. doi: 10.1002/ijc.31014. Epub 2017 Sep 13. Int J Cancer. 2018. PMID: 28836271 Free PMC article. Review.
469 results