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Obesity caused by an OVOL2 mutation reveals dual roles of OVOL2 in promoting thermogenesis and limiting white adipogenesis.
Zhang Z, Jiang Y, Su L, Ludwig S, Zhang X, Tang M, Li X, Anderton P, Zhan X, Choi M, Russell J, Bu CH, Lyon S, Xu D, Hildebrand S, Scott L, Quan J, Simpson R, Sun Q, Qin B, Collie T, Tadesse M, Moresco EMY, Beutler B. Zhang Z, et al. Among authors: li x. Cell Metab. 2022 Nov 1;34(11):1860-1874.e4. doi: 10.1016/j.cmet.2022.09.018. Epub 2022 Oct 12. Cell Metab. 2022. PMID: 36228616 Free PMC article.
Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet.
Krebs P, Fan W, Chen YH, Tobita K, Downes MR, Wood MR, Sun L, Li X, Xia Y, Ding N, Spaeth JM, Moresco EM, Boyer TG, Lo CW, Yen J, Evans RM, Beutler B. Krebs P, et al. Among authors: li x. Proc Natl Acad Sci U S A. 2011 Dec 6;108(49):19678-82. doi: 10.1073/pnas.1117835108. Epub 2011 Nov 21. Proc Natl Acad Sci U S A. 2011. PMID: 22106289 Free PMC article.
ZBTB1 is a determinant of lymphoid development.
Siggs OM, Li X, Xia Y, Beutler B. Siggs OM, et al. Among authors: li x. J Exp Med. 2012 Jan 16;209(1):19-27. doi: 10.1084/jem.20112084. Epub 2011 Dec 26. J Exp Med. 2012. PMID: 22201126 Free PMC article.
MAVS, cGAS, and endogenous retroviruses in T-independent B cell responses.
Zeng M, Hu Z, Shi X, Li X, Zhan X, Li XD, Wang J, Choi JH, Wang KW, Purrington T, Tang M, Fina M, DeBerardinis RJ, Moresco EM, Pedersen G, McInerney GM, Karlsson Hedestam GB, Chen ZJ, Beutler B. Zeng M, et al. Among authors: li x, li xd. Science. 2014 Dec 19;346(6216):1486-92. doi: 10.1126/science.346.6216.1486. Science. 2014. Retraction in: Science. 2017 Oct 27;358(6362):458. doi: 10.1126/science.aar2406 PMID: 25525240 Free PMC article. Retracted.
Real-time resolution of point mutations that cause phenovariance in mice.
Wang T, Zhan X, Bu CH, Lyon S, Pratt D, Hildebrand S, Choi JH, Zhang Z, Zeng M, Wang KW, Turer E, Chen Z, Zhang D, Yue T, Wang Y, Shi H, Wang J, Sun L, SoRelle J, McAlpine W, Hutchins N, Zhan X, Fina M, Gobert R, Quan J, Kreutzer M, Arnett S, Hawkins K, Leach A, Tate C, Daniel C, Reyna C, Prince L, Davis S, Purrington J, Bearden R, Weatherly J, White D, Russell J, Sun Q, Tang M, Li X, Scott L, Moresco EM, McInerney GM, Karlsson Hedestam GB, Xie Y, Beutler B. Wang T, et al. Among authors: li x. Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):E440-9. doi: 10.1073/pnas.1423216112. Epub 2015 Jan 20. Proc Natl Acad Sci U S A. 2015. PMID: 25605905 Free PMC article.
NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component.
Shi H, Wang Y, Li X, Zhan X, Tang M, Fina M, Su L, Pratt D, Bu CH, Hildebrand S, Lyon S, Scott L, Quan J, Sun Q, Russell J, Arnett S, Jurek P, Chen D, Kravchenko VV, Mathison JC, Moresco EM, Monson NL, Ulevitch RJ, Beutler B. Shi H, et al. Among authors: li x. Nat Immunol. 2016 Mar;17(3):250-8. doi: 10.1038/ni.3333. Epub 2015 Dec 7. Nat Immunol. 2016. PMID: 26642356 Free PMC article.
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