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ONC213: a novel strategy to resensitize resistant AML cells to venetoclax through induction of mitochondrial stress.
Carter JL, Su Y, Al-Antary ET, Zhao J, Qiao X, Wang G, Edwards H, Polin L, Kushner J, Dzinic SH, White K, Buck SA, Hüttemann M, Allen JE, Prabhu VV, Yang J, Taub JW, Ge Y. Carter JL, et al. Among authors: buck sa. J Exp Clin Cancer Res. 2025 Jan 9;44(1):10. doi: 10.1186/s13046-024-03267-6. J Exp Clin Cancer Res. 2025. PMID: 39780285 Free PMC article.
The OCT2/MATE1 Interaction Between Trifluridine, Metformin and Cimetidine: A Crossover Pharmacokinetic Study.
Guchelaar NAD, Buck SAJ, van Doorn L, Hussaarts KGAM, Sandberg Y, van der Padt-Pruijsten A, van Alphen RJ, Poppe-Manenschijn L, Vleut I, de Bruijn P, van Leeuwen RWF, Mostert B, Eskens FALM, Oomen-de Hoop E, Koolen SLW, Mathijssen RHJ. Guchelaar NAD, et al. Among authors: buck saj. Clin Pharmacokinet. 2024 Jul;63(7):1037-1044. doi: 10.1007/s40262-024-01390-3. Epub 2024 Jun 28. Clin Pharmacokinet. 2024. PMID: 38951433 Free PMC article. Clinical Trial.
Darolutamide does not interfere with OATP-mediated uptake of docetaxel.
Buck SAJ, Talebi Z, Drabison T, Jin Y, Gibson AA, Hu P, de Bruijn P, de Ridder CMA, Stuurman D, Hu S, van Weerden WM, Koolen SLW, de Wit R, Sparreboom A, Mathijssen RHJ, Eisenmann ED. Buck SAJ, et al. Int J Cancer. 2024 Jul 15;155(2):314-323. doi: 10.1002/ijc.34922. Epub 2024 Mar 16. Int J Cancer. 2024. PMID: 38491867
The Imipridone ONC213 Targets α-Ketoglutarate Dehydrogenase to Induce Mitochondrial Stress and Suppress Oxidative Phosphorylation in Acute Myeloid Leukemia.
Su Y, Carter JL, Li X, Fukuda Y, Gray A, Lynch J, Edwards H, Ma J, Schreiner P, Polin L, Kushner J, Dzinic SH, Buck SA, Pruett-Miller SM, Hege-Hurrish K, Robinson C, Qiao X, Liu S, Wu S, Wang G, Li J, Allen JE, Prabhu VV, Schimmer AD, Joshi D, Kalhor-Monfared S, Watson IDG, Marcellus R, Isaac MB, Al-Awar R, Taub JW, Lin H, Schuetz JD, Ge Y. Su Y, et al. Among authors: buck sa. Cancer Res. 2024 Apr 1;84(7):1084-1100. doi: 10.1158/0008-5472.CAN-23-2659. Cancer Res. 2024. PMID: 38266099 Free PMC article.
65 results