Intrinsic disorder in dynein intermediate chain modulates its interactions with NudE and dynactin.
Nyarko A, Song Y, Barbar E.
Nyarko A, et al. Among authors: barbar e.
J Biol Chem. 2012 Jul 20;287(30):24884-93. doi: 10.1074/jbc.M112.376038. Epub 2012 Jun 5.
J Biol Chem. 2012.
PMID: 22669947
Free PMC article.
Although the IC binding domains of both NudE and p150(Glued) form dimeric coiled-coils and bind IC at a common site, we observe distinct binding modes for each regulatory protein: 1) NudE binds region 1 of the bi-segmental binding footprint of p150(Glued), whereas p150(Glued) req …
Although the IC binding domains of both NudE and p150(Glued) form dimeric coiled-coils and bind IC at a common site, we observe distinct bin …