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Neutrophil "plucking" on megakaryocytes drives platelet production and boosts cardiovascular disease.
Petzold T, Zhang Z, Ballesteros I, Saleh I, Polzin A, Thienel M, Liu L, Ul Ain Q, Ehreiser V, Weber C, Kilani B, Mertsch P, Götschke J, Cremer S, Fu W, Lorenz M, Ishikawa-Ankerhold H, Raatz E, El-Nemr S, Görlach A, Marhuenda E, Stark K, Pircher J, Stegner D, Gieger C, Schmidt-Supprian M, Gaertner F, Almendros I, Kelm M, Schulz C, Hidalgo A, Massberg S. Petzold T, et al. Among authors: massberg s. Immunity. 2022 Dec 13;55(12):2285-2299.e7. doi: 10.1016/j.immuni.2022.10.001. Epub 2022 Oct 21. Immunity. 2022. PMID: 36272416 Free PMC article.
Platelets secrete stromal cell-derived factor 1alpha and recruit bone marrow-derived progenitor cells to arterial thrombi in vivo.
Massberg S, Konrad I, Schürzinger K, Lorenz M, Schneider S, Zohlnhoefer D, Hoppe K, Schiemann M, Kennerknecht E, Sauer S, Schulz C, Kerstan S, Rudelius M, Seidl S, Sorge F, Langer H, Peluso M, Goyal P, Vestweber D, Emambokus NR, Busch DH, Frampton J, Gawaz M. Massberg S, et al. J Exp Med. 2006 May 15;203(5):1221-33. doi: 10.1084/jem.20051772. Epub 2006 Apr 17. J Exp Med. 2006. PMID: 16618794 Free PMC article.
574 results