O'Brien S - Search Results

1

SCF^FBXW7 regulates G2-M progression through control of CCNL1 ubiquitination.

O'Brien S, Kelso S, Steinhart Z, Orlicky S, Mis M, Kim Y, Lin S, Sicheri F, Angers S. O'Brien S, et al. EMBO Rep. 2022 Dec 6;23(12):e55044. doi: 10.15252/embr.202255044. Epub 2022 Oct 24. EMBO Rep. 2022. PMID: 36278408 Free PMC article.

2

Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice.

Tao Y, Mis M, Blazer L, Ustav M Jnr, Steinhart Z, Chidiac R, Kubarakos E, O'Brien S, Wang X, Jarvik N, Patel N, Adams J, Moffat J, Angers S, Sidhu SS. Tao Y, et al. Elife. 2019 Aug 27;8:e46134. doi: 10.7554/eLife.46134. Elife. 2019. PMID: 31452509 Free PMC article.

3

IPO11 mediates βcatenin nuclear import in a subset of colorectal cancers.

Mis M, O'Brien S, Steinhart Z, Lin S, Hart T, Moffat J, Angers S. Mis M, et al. J Cell Biol. 2020 Feb 3;219(2):e201903017. doi: 10.1083/jcb.201903017. J Cell Biol. 2020. PMID: 31881079 Free PMC article.

4

Crystal structure of the CDK11 kinase domain bound to the small-molecule inhibitor OTS964.

Kelso S, O'Brien S, Kurinov I, Angers S, Sicheri F. Kelso S, et al. Structure. 2022 Dec 1;30(12):1615-1625.e4. doi: 10.1016/j.str.2022.10.003. Epub 2022 Nov 2. Structure. 2022. PMID: 36327972 Free PMC article.

5

Modulation of Wnt-β-catenin signaling with antibodies: therapeutic opportunities and challenges.

O'Brien S, Chidiac R, Angers S. O'Brien S, et al. Trends Pharmacol Sci. 2023 Jun;44(6):354-365. doi: 10.1016/j.tips.2023.03.008. Epub 2023 Apr 19. Trends Pharmacol Sci. 2023. PMID: 37085400 Review.

6

Relative Biological Effectiveness (RBE) of [⁶⁴Cu]Cu and [¹⁷⁷Lu]Lu-NOTA-panitumumab F (ab')₂ radioimmunotherapeutic agents vs. γ-radiation for decreasing the clonogenic survival in vitro of human pancreatic ductal adenocarcinoma (PDAC) cells.

Boyle AJ, Cai Z, O'Brien S, Crick J, Angers S, Reilly RM. Boyle AJ, et al. Nucl Med Biol. 2023 Jul-Aug;122-123:108367. doi: 10.1016/j.nucmedbio.2023.108367. Epub 2023 Jul 17. Nucl Med Biol. 2023. PMID: 37506639

7

FBXW7-loss Sensitizes Cells to ATR Inhibition Through Induced Mitotic Catastrophe.

O'Brien S, Ubhi T, Wolf L, Gandhi K, Lin S, Chaudary N, Dhani NC, Milosevic M, Brown GW, Angers S. O'Brien S, et al. Cancer Res Commun. 2023 Dec 21;3(12):2596-2607. doi: 10.1158/2767-9764.CRC-23-0306. Cancer Res Commun. 2023. PMID: 38032106 Free PMC article.

8

CRISPR Screening in Tandem with Targeted mtDNA Damage Reveals WRNIP1 Essentiality.

Sack T, Dhavarasa P, Szames D, O'Brien S, Angers S, Kelley SO. Sack T, et al. ACS Chem Biol. 2023 Dec 15;18(12):2599-2609. doi: 10.1021/acschembio.3c00620. Epub 2023 Dec 6. ACS Chem Biol. 2023. PMID: 38054633

9

Linking Foraging Behaviour and Habitat Preferences During Moult Across Multiple Populations of Red-Throated Diver.

Duckworth J, O'Brien S, Dunn RE, Petersen IK, Petersen A, Benediktsson G, Johnson L, Lehikoinen P, Okill DJ, Väisänen R, Williams J, Williams S, Daunt F, Green JA. Duckworth J, et al. Among authors: o brien s. Ecol Evol. 2024 Dec 23;14(12):e70733. doi: 10.1002/ece3.70733. eCollection 2024 Dec. Ecol Evol. 2024. PMID: 39717643 Free PMC article.

10

Relationship Between Severity of Ischemia and Coronary Artery Disease for Different Stress Test Modalities in the ISCHEMIA Trial.

Reynolds HR, Page CB, Shaw LJ, Berman DS, Chaitman BR, Picard MH, Kwong RY, Min JK, Leipsic J, Mancini GBJ, Budoff MJ, Hague CJ, Senior R, Szwed H, Bhargava B, Celutkiene J, Gadkari M, Bainey KR, Doerr R, Ramos RB, Ong P, Naik SR, Steg PG, Goetschalckx K, Chow BJW, Scherrer-Crosbie M, Phillips L, Mark DB, Spertus JA, Alexander KP, O'Brien SM, Boden WE, Bangalore S, Stone GW, Maron DJ, Hochman JS; ISCHEMIA Research Group. Reynolds HR, et al. Among authors: o brien sm. Circ Cardiovasc Interv. 2024 Dec;17(12):e013743. doi: 10.1161/CIRCINTERVENTIONS.123.013743. Epub 2024 Dec 17. Circ Cardiovasc Interv. 2024. PMID: 39689188 Clinical Trial.

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