Radford SE - Search Results

1

Probing RNA Conformations Using a Polymer-Electrolyte Solid-State Nanopore.

Chau C, Marcuccio F, Soulias D, Edwards MA, Tuplin A, Radford SE, Hewitt E, Actis P. Chau C, et al. Among authors: radford se. ACS Nano. 2022 Dec 27;16(12):20075-20085. doi: 10.1021/acsnano.2c08312. Epub 2022 Oct 24. ACS Nano. 2022. PMID: 36279181 Free PMC article.

2

Competing pathways determine fibril morphology in the self-assembly of beta2-microglobulin into amyloid.

Gosal WS, Morten IJ, Hewitt EW, Smith DA, Thomson NH, Radford SE. Gosal WS, et al. Among authors: radford se. J Mol Biol. 2005 Aug 26;351(4):850-64. doi: 10.1016/j.jmb.2005.06.040. J Mol Biol. 2005. PMID: 16024039

3

A systematic study of the effect of physiological factors on beta2-microglobulin amyloid formation at neutral pH.

Myers SL, Jones S, Jahn TR, Morten IJ, Tennent GA, Hewitt EW, Radford SE. Myers SL, et al. Among authors: radford se. Biochemistry. 2006 Feb 21;45(7):2311-21. doi: 10.1021/bi052434i. Biochemistry. 2006. PMID: 16475820

4

Specific glycosaminoglycans promote unseeded amyloid formation from beta2-microglobulin under physiological conditions.

Borysik AJ, Morten IJ, Radford SE, Hewitt EW. Borysik AJ, et al. Among authors: radford se. Kidney Int. 2007 Jul;72(2):174-81. doi: 10.1038/sj.ki.5002270. Epub 2007 May 2. Kidney Int. 2007. PMID: 17495865 Free article.

5

Investigation into the role of macrophages in the formation and degradation of beta2-microglobulin amyloid fibrils.

Morten IJ, Gosal WS, Radford SE, Hewitt EW. Morten IJ, et al. Among authors: radford se. J Biol Chem. 2007 Oct 5;282(40):29691-700. doi: 10.1074/jbc.M705004200. Epub 2007 Aug 8. J Biol Chem. 2007. PMID: 17686767 Free article.

6

Fibril fragmentation enhances amyloid cytotoxicity.

Xue WF, Hellewell AL, Gosal WS, Homans SW, Hewitt EW, Radford SE. Xue WF, et al. Among authors: radford se. J Biol Chem. 2009 Dec 4;284(49):34272-82. doi: 10.1074/jbc.M109.049809. Epub 2009 Oct 6. J Biol Chem. 2009. PMID: 19808677 Free PMC article.

7

Fibril fragmentation in amyloid assembly and cytotoxicity: when size matters.

Xue WF, Hellewell AL, Hewitt EW, Radford SE. Xue WF, et al. Among authors: radford se. Prion. 2010 Jan-Mar;4(1):20-5. doi: 10.4161/pri.4.1.11378. Epub 2010 Jan 29. Prion. 2010. PMID: 20305394 Free PMC article.

8

Ligand binding to distinct states diverts aggregation of an amyloid-forming protein.

Woods LA, Platt GW, Hellewell AL, Hewitt EW, Homans SW, Ashcroft AE, Radford SE. Woods LA, et al. Among authors: radford se. Nat Chem Biol. 2011 Aug 28;7(10):730-9. doi: 10.1038/nchembio.635. Nat Chem Biol. 2011. PMID: 21873994 Free PMC article.

9

Characterization of the response of primary cells relevant to dialysis-related amyloidosis to β2-microglobulin monomer and fibrils.

Porter MY, Routledge KE, Radford SE, Hewitt EW. Porter MY, et al. Among authors: radford se. PLoS One. 2011;6(11):e27353. doi: 10.1371/journal.pone.0027353. Epub 2011 Nov 9. PLoS One. 2011. PMID: 22096558 Free PMC article.

10

Direct three-dimensional visualization of membrane disruption by amyloid fibrils.

Milanesi L, Sheynis T, Xue WF, Orlova EV, Hellewell AL, Jelinek R, Hewitt EW, Radford SE, Saibil HR. Milanesi L, et al. Among authors: radford se. Proc Natl Acad Sci U S A. 2012 Dec 11;109(50):20455-60. doi: 10.1073/pnas.1206325109. Epub 2012 Nov 26. Proc Natl Acad Sci U S A. 2012. PMID: 23184970 Free PMC article.

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