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A FOXO1-dependent transcription network is a targetable vulnerability of mantle cell lymphomas.
Jang JY, Hwang I, Pan H, Yao J, Alinari L, Imada E, Zanettini C, Kluk MJ, Wang Y, Lee Y, Lin HV, Huang X, Di Liberto M, Chen Z, Ballman KV, Cantley LC, Marchionni L, Inghirami G, Elemento O, Baiocchi RA, Chen-Kiang S, Belvedere S, Zheng H, Paik J. Jang JY, et al. Among authors: chen z, chen kiang s. J Clin Invest. 2022 Dec 15;132(24):e160767. doi: 10.1172/JCI160767. J Clin Invest. 2022. PMID: 36282572 Free PMC article.
ZNF365 promotes stability of fragile sites and telomeres.
Zhang Y, Shin SJ, Liu D, Ivanova E, Foerster F, Ying H, Zheng H, Xiao Y, Chen Z, Protopopov A, Depinho RA, Paik JH. Zhang Y, et al. Among authors: chen z. Cancer Discov. 2013 Jul;3(7):798-811. doi: 10.1158/2159-8290.CD-12-0536. Epub 2013 Jun 17. Cancer Discov. 2013. PMID: 23776040 Free PMC article.
Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH.
Yun J, Mullarky E, Lu C, Bosch KN, Kavalier A, Rivera K, Roper J, Chio II, Giannopoulou EG, Rago C, Muley A, Asara JM, Paik J, Elemento O, Chen Z, Pappin DJ, Dow LE, Papadopoulos N, Gross SS, Cantley LC. Yun J, et al. Among authors: chen z. Science. 2015 Dec 11;350(6266):1391-6. doi: 10.1126/science.aaa5004. Epub 2015 Nov 5. Science. 2015. PMID: 26541605 Free PMC article.
Postibrutinib outcomes in patients with mantle cell lymphoma.
Martin P, Maddocks K, Leonard JP, Ruan J, Goy A, Wagner-Johnston N, Rule S, Advani R, Iberri D, Phillips T, Spurgeon S, Kozin E, Noto K, Chen Z, Jurczak W, Auer R, Chmielowska E, Stilgenbauer S, Bloehdorn J, Portell C, Williams ME, Dreyling M, Barr PM, Chen-Kiang S, DiLiberto M, Furman RR, Blum KA. Martin P, et al. Among authors: chen z, chen kiang s. Blood. 2016 Mar 24;127(12):1559-63. doi: 10.1182/blood-2015-10-673145. Epub 2016 Jan 13. Blood. 2016. PMID: 26764355 Free article.
UCHL1 loss alters the cell-cycle in metastatic pancreatic neuroendocrine tumors.
Finnerty BM, Moore MD, Verma A, Aronova A, Huang S, Edwards DP, Chen Z, Seandel M, Scognamiglio T, Du YN, Elemento O, Zarnegar R, Min IM, Fahey TJ. Finnerty BM, et al. Among authors: chen z. Endocr Relat Cancer. 2019 Apr 1;26(4):411-423. doi: 10.1530/ERC-18-0507. Epub 2019 Jan 1. Endocr Relat Cancer. 2019. PMID: 30689542
A phase 1 trial of ibrutinib plus palbociclib in previously treated mantle cell lymphoma.
Martin P, Bartlett NL, Blum KA, Park S, Maddocks K, Ruan J, Ridling L, Dittus C, Chen Z, Huang X, Inghirami G, DiLiberto M, Chen-Kiang S, Leonard JP. Martin P, et al. Among authors: chen z, chen kiang s. Blood. 2019 Mar 14;133(11):1201-1204. doi: 10.1182/blood-2018-11-886457. Epub 2019 Jan 28. Blood. 2019. PMID: 30692121 Free PMC article. Clinical Trial.
Function and clinical relevance of RHAMM isoforms in pancreatic tumor progression.
Choi S, Wang D, Chen X, Tang LH, Verma A, Chen Z, Kim BJ, Selesner L, Robzyk K, Zhang G, Pang S, Han T, Chan CS, Fahey TJ 3rd, Elemento O, Du YN. Choi S, et al. Among authors: chen z, chen x. Mol Cancer. 2019 May 9;18(1):92. doi: 10.1186/s12943-019-1018-y. Mol Cancer. 2019. PMID: 31072393 Free PMC article.
Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis.
Li M, Chiang YL, Lyssiotis CA, Teater MR, Hong JY, Shen H, Wang L, Hu J, Jing H, Chen Z, Jain N, Duy C, Mistry SJ, Cerchietti L, Cross JR, Cantley LC, Green MR, Lin H, Melnick AM. Li M, et al. Among authors: chen z. Cancer Cell. 2019 Jun 10;35(6):916-931.e9. doi: 10.1016/j.ccell.2019.05.002. Cancer Cell. 2019. PMID: 31185214 Free PMC article.
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