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Pharmacological conversion of gut epithelial cells into insulin-producing cells lowers glycemia in diabetic animals.
Du W, Wang J, Kuo T, Wang L, McKimpson WM, Son J, Watanabe H, Kitamoto T, Lee Y, Creusot RJ, Ratner LE, McCune K, Chen YW, Grubbs BH, Thornton ME, Fan J, Sultana N, Diaz BS, Balasubramanian I, Gao N, Belvedere S, Accili D. Du W, et al. Among authors: balasubramanian i. J Clin Invest. 2022 Dec 15;132(24):e162720. doi: 10.1172/JCI162720. J Clin Invest. 2022. PMID: 36282594 Free PMC article.
Paneth Cell Multipotency Induced by Notch Activation following Injury.
Yu S, Tong K, Zhao Y, Balasubramanian I, Yap GS, Ferraris RP, Bonder EM, Verzi MP, Gao N. Yu S, et al. Among authors: balasubramanian i. Cell Stem Cell. 2018 Jul 5;23(1):46-59.e5. doi: 10.1016/j.stem.2018.05.002. Epub 2018 Jun 7. Cell Stem Cell. 2018. PMID: 29887318 Free PMC article.
The arginine and nitric oxide metabolic pathway regulate the gut colonization and expansion of Ruminococcous gnavus.
Flores JA, Antonio JM, Suntornsaratoon P, Meadows V, Bandyopadhyay S, Han J, Singh R, Balasubramanian I, Upadhyay R, Liu Y, Bonder EM, Kiela P, Su X, Ferraris R, Gao N. Flores JA, et al. Among authors: balasubramanian i. J Biol Chem. 2024 Sep;300(9):107614. doi: 10.1016/j.jbc.2024.107614. Epub 2024 Jul 31. J Biol Chem. 2024. PMID: 39089585 Free PMC article.
Macrophage LRRK2 hyperactivity impairs autophagy and induces Paneth cell dysfunction.
Sun S, Hodel M, Wang X, De Vicente J, Haritunians T, Debebe A, Hung CT, Ma C, Malique A, Nguyen HN, Agam M, Maloney MT, Goo MS, Kluss JH, Mishra R, Frein J, Foster A, Ballentine S, Pandey U, Kern J, Yang S, Mengesha E, Balasubramanian I, Arguello A, Estrada AA, Gao N, Peter I, McGovern DPB, Henry AG, Stappenbeck TS, Liu TC. Sun S, et al. Among authors: balasubramanian i. Sci Immunol. 2024 Nov 8;9(101):eadi7907. doi: 10.1126/sciimmunol.adi7907. Epub 2024 Nov 8. Sci Immunol. 2024. PMID: 39514635
67 results