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Hypoxia-inducible factor-1α plays roles in Epstein-Barr virus's natural life cycle and tumorigenesis by inducing lytic infection through direct binding to the immediate-early BZLF1 gene promoter.
Kraus RJ, Yu X, Cordes BA, Sathiamoorthi S, Iempridee T, Nawandar DM, Ma S, Romero-Masters JC, McChesney KG, Lin Z, Makielski KR, Lee DL, Lambert PF, Johannsen EC, Kenney SC, Mertz JE. Kraus RJ, et al. PLoS Pathog. 2017 Jun 15;13(6):e1006404. doi: 10.1371/journal.ppat.1006404. eCollection 2017 Jun. PLoS Pathog. 2017. PMID: 28617871 Free PMC article.
MmuPV1 E6 induces cell proliferation and other hallmarks of cancer.
Romero-Masters JC, Muehlbauer LK, Hayes M, Grace M, Shishkova E, Coon JJ, Munger K, Lambert PF. Romero-Masters JC, et al. mBio. 2023 Dec 19;14(6):e0245823. doi: 10.1128/mbio.02458-23. Epub 2023 Oct 31. mBio. 2023. PMID: 37905801 Free PMC article.
Development of a novel inducer for EBV lytic therapy.
Tikhmyanova N, Paparoidamis N, Romero-Masters J, Feng X, Mohammed FS, Reddy PAN, Kenney SC, Lieberman PM, Salvino JM. Tikhmyanova N, et al. Bioorg Med Chem Lett. 2019 Aug 15;29(16):2259-2264. doi: 10.1016/j.bmcl.2019.06.034. Epub 2019 Jun 22. Bioorg Med Chem Lett. 2019. PMID: 31255485 Free PMC article.
EBNA2-deleted Epstein-Barr virus (EBV) isolate, P3HR1, causes Hodgkin-like lymphomas and diffuse large B cell lymphomas with type II and Wp-restricted latency types in humanized mice.
Li C, Romero-Masters JC, Huebner S, Ohashi M, Hayes M, Bristol JA, Nelson SE, Eichelberg MR, Van Sciver N, Ranheim EA, Scott RS, Johannsen EC, Kenney SC. Li C, et al. Among authors: romero masters jc. PLoS Pathog. 2020 Jun 15;16(6):e1008590. doi: 10.1371/journal.ppat.1008590. eCollection 2020 Jun. PLoS Pathog. 2020. PMID: 32542010 Free PMC article.
Reduced IRF4 expression promotes lytic phenotype in Type 2 EBV-infected B cells.
Bristol JA, Brand J, Ohashi M, Eichelberg MR, Casco A, Nelson SE, Hayes M, Romero-Masters JC, Baiu DC, Gumperz JE, Johannsen EC, Dinh HQ, Kenney SC. Bristol JA, et al. Among authors: romero masters jc. PLoS Pathog. 2022 Apr 26;18(4):e1010453. doi: 10.1371/journal.ppat.1010453. eCollection 2022 Apr. PLoS Pathog. 2022. PMID: 35472072 Free PMC article.
A cancer-associated Epstein-Barr virus BZLF1 promoter variant enhances lytic infection.
Bristol JA, Djavadian R, Albright ER, Coleman CB, Ohashi M, Hayes M, Romero-Masters JC, Barlow EA, Farrell PJ, Rochford R, Kalejta RF, Johannsen EC, Kenney SC. Bristol JA, et al. Among authors: romero masters jc. PLoS Pathog. 2018 Jul 27;14(7):e1007179. doi: 10.1371/journal.ppat.1007179. eCollection 2018 Jul. PLoS Pathog. 2018. PMID: 30052684 Free PMC article.
16 results