Bargsten K - Search Results

1

Structural basis for Cas9 off-target activity.

Pacesa M, Lin CH, Cléry A, Saha A, Arantes PR, Bargsten K, Irby MJ, Allain FH, Palermo G, Cameron P, Donohoue PD, Jinek M. Pacesa M, et al. Among authors: bargsten k. Cell. 2022 Oct 27;185(22):4067-4081.e21. doi: 10.1016/j.cell.2022.09.026. Cell. 2022. PMID: 36306733 Free PMC article.

2

Structural Plasticity of PAM Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9.

Anders C, Bargsten K, Jinek M. Anders C, et al. Among authors: bargsten k. Mol Cell. 2016 Mar 17;61(6):895-902. doi: 10.1016/j.molcel.2016.02.020. Mol Cell. 2016. PMID: 26990992 Free PMC article.

3

Covalent linkage of the DNA repair template to the CRISPR-Cas9 nuclease enhances homology-directed repair.

Savic N, Ringnalda FC, Lindsay H, Berk C, Bargsten K, Li Y, Neri D, Robinson MD, Ciaudo C, Hall J, Jinek M, Schwank G. Savic N, et al. Among authors: bargsten k. Elife. 2018 May 29;7:e33761. doi: 10.7554/eLife.33761. Elife. 2018. PMID: 29809142 Free PMC article.

4

In vitro Generation of CRISPR-Cas9 Complexes with Covalently Bound Repair Templates for Genome Editing in Mammalian Cells.

Savić N, Ringnalda FC, Berk C, Bargsten K, Hall J, Jinek M, Schwank G. Savić N, et al. Among authors: bargsten k. Bio Protoc. 2019 Jan 5;9(1):e3136. doi: 10.21769/BioProtoc.3136. Bio Protoc. 2019. PMID: 30675496 Free PMC article.

5

Molecular mechanism of the RNA helicase DHX37 and its activation by UTP14A in ribosome biogenesis.

Boneberg FM, Brandmann T, Kobel L, van den Heuvel J, Bargsten K, Bammert L, Kutay U, Jinek M. Boneberg FM, et al. Among authors: bargsten k. RNA. 2019 Jun;25(6):685-701. doi: 10.1261/rna.069609.118. Epub 2019 Mar 25. RNA. 2019. PMID: 30910870 Free PMC article.

6

Corrigendum: Molecular mechanism of the RNA helicase DHX37 and its activation by UTP14A in ribosome biogenesis.

Boneberg FM, Brandmann T, Kobel L, van den Heuvel J, Bargsten K, Bammert L, Kutay U, Jinek M. Boneberg FM, et al. Among authors: bargsten k. RNA. 2019 Nov;25(11):1576. doi: 10.1261/rna.072900.119. RNA. 2019. PMID: 31619564 Free PMC article. No abstract available.

7

Structural basis of tubulin tyrosination by tubulin tyrosine ligase.

Prota AE, Magiera MM, Kuijpers M, Bargsten K, Frey D, Wieser M, Jaussi R, Hoogenraad CC, Kammerer RA, Janke C, Steinmetz MO. Prota AE, et al. Among authors: bargsten k. J Cell Biol. 2013 Feb 4;200(3):259-70. doi: 10.1083/jcb.201211017. Epub 2013 Jan 28. J Cell Biol. 2013. PMID: 23358242 Free PMC article.

8

Structural Basis of Microtubule Stabilization by Discodermolide.

Prota AE, Bargsten K, Redondo-Horcajo M, Smith AB 3rd, Yang CH, McDaid HM, Paterson I, Horwitz SB, Fernando Díaz J, Steinmetz MO. Prota AE, et al. Among authors: bargsten k. Chembiochem. 2017 May 18;18(10):905-909. doi: 10.1002/cbic.201600696. Epub 2017 Mar 27. Chembiochem. 2017. PMID: 28207984 Free PMC article.

9

Structural basis of microtubule stabilization by laulimalide and peloruside A.

Prota AE, Bargsten K, Northcote PT, Marsh M, Altmann KH, Miller JH, Díaz JF, Steinmetz MO. Prota AE, et al. Among authors: bargsten k. Angew Chem Int Ed Engl. 2014 Feb 3;53(6):1621-5. doi: 10.1002/anie.201307749. Epub 2014 Jan 27. Angew Chem Int Ed Engl. 2014. PMID: 24470331

10

Structural Basis of Noscapine Activation for Tubulin Binding.

Oliva MA, Prota AE, Rodríguez-Salarichs J, Bennani YL, Jiménez-Barbero J, Bargsten K, Canales Á, Steinmetz MO, Díaz JF. Oliva MA, et al. Among authors: bargsten k. J Med Chem. 2020 Aug 13;63(15):8495-8501. doi: 10.1021/acs.jmedchem.0c00855. Epub 2020 Jul 29. J Med Chem. 2020. PMID: 32657585 Free article.

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