Al-Karmalawy AA - Search Results

1

Biological evaluation, docking studies, and in silico ADME prediction of some pyrimidine and pyridine derivatives as potential EGFR^WT and EGFR^T790M inhibitors.

Al-Warhi T, Al-Karmalawy AA, Elmaaty AA, Alshubramy MA, Abdel-Motaal M, Majrashi TA, Asem M, Nabil A, Eldehna WM, Sharaky M. Al-Warhi T, et al. J Enzyme Inhib Med Chem. 2023 Dec;38(1):176-191. doi: 10.1080/14756366.2022.2135512. J Enzyme Inhib Med Chem. 2023. PMID: 36317648 Free PMC article.

2

SARS-CoV-2 Genetic Diversity and Lineage Dynamics in Egypt during the First 18 Months of the Pandemic.

Roshdy WH, Khalifa MK, San JE, Tegally H, Wilkinson E, Showky S, Martin DP, Moir M, Naguib A, Elguindy N, Gomaa MR, Fahim M, Abu Elsood H, Mohsen A, Galal R, Hassany M, Lessells RJ, Al-Karmalawy AA, El-Shesheny R, Kandeil AM, Ali MA, de Oliveira T. Roshdy WH, et al. Viruses. 2022 Aug 25;14(9):1878. doi: 10.3390/v14091878. Viruses. 2022. PMID: 36146685 Free PMC article.

3

Effect of Vitamin D supplementation in patients with liver cirrhosis having spontaneous bacterial peritonitis: a randomized controlled study.

Mohamed AA, Al-Karmalawy AA, El-Kholy AA, El-Damas DA, Abostate HM, Mostafa SM, Hamada M, Khalik Elkady MA, Hassan Y, Al-Hussain E, Khalil MG, Badawy I, Elebeedy D, Alsfouk BA, Shaheenl MM. Mohamed AA, et al. Eur Rev Med Pharmacol Sci. 2021 Nov;25(22):6908-6919. doi: 10.26355/eurrev_202111_27239. Eur Rev Med Pharmacol Sci. 2021. PMID: 34859852 Free article. Clinical Trial.

4

Design, synthesis, molecular docking, and anticancer activity of benzoxazole derivatives as VEGFR-2 inhibitors.

El-Helby AA, Sakr H, Eissa IH, Abulkhair H, Al-Karmalawy AA, El-Adl K. El-Helby AA, et al. Arch Pharm (Weinheim). 2019 Oct;352(10):e1900113. doi: 10.1002/ardp.201900113. Epub 2019 Aug 25. Arch Pharm (Weinheim). 2019. PMID: 31448458

5

In a search for potential drug candidates for combating COVID-19: computational study revealed salvianolic acid B as a potential therapeutic targeting 3CLpro and spike proteins.

Elmaaty AA, Darwish KM, Khattab M, Elhady SS, Salah M, Hamed MIA, Al-Karmalawy AA, Saleh MM. Elmaaty AA, et al. J Biomol Struct Dyn. 2022;40(19):8866-8893. doi: 10.1080/07391102.2021.1918256. Epub 2021 Apr 30. J Biomol Struct Dyn. 2022. PMID: 33928870

6

From triazolophthalazines to triazoloquinazolines: A bioisosterism-guided approach toward the identification of novel PCAF inhibitors with potential anticancer activity.

El-Shershaby MH, Ghiaty A, Bayoumi AH, Al-Karmalawy AA, Husseiny EM, El-Zoghbi MS, Abulkhair HS. El-Shershaby MH, et al. Bioorg Med Chem. 2021 Jul 15;42:116266. doi: 10.1016/j.bmc.2021.116266. Epub 2021 Jun 5. Bioorg Med Chem. 2021. PMID: 34126285

7

Design, Synthesis, Biological Evaluation, 2D-QSAR Modeling, and Molecular Docking Studies of Novel 1H-3-Indolyl Derivatives as Significant Antioxidants.

Aziz MA, Shehab WS, Al-Karmalawy AA, El-Farargy AF, Abdellattif MH. Aziz MA, et al. Int J Mol Sci. 2021 Sep 27;22(19):10396. doi: 10.3390/ijms221910396. Int J Mol Sci. 2021. PMID: 34638734 Free PMC article.

8

Topo II inhibition and DNA intercalation by new phthalazine-based derivatives as potent anticancer agents: design, synthesis, anti-proliferative, docking, and in vivo studies.

Khalifa MM, Al-Karmalawy AA, Elkaeed EB, Nafie MS, Tantawy MA, Eissa IH, Mahdy HA. Khalifa MM, et al. J Enzyme Inhib Med Chem. 2022 Dec;37(1):299-314. doi: 10.1080/14756366.2021.2007905. J Enzyme Inhib Med Chem. 2022. PMID: 34894955 Free PMC article.

9

In vitro and computational insights revealing the potential inhibitory effect of Tanshinone IIA against influenza A virus.

Elebeedy D, Badawy I, Elmaaty AA, Saleh MM, Kandeil A, Ghanem A, Kutkat O, Alnajjar R, Abd El Maksoud AI, Al-Karmalawy AA. Elebeedy D, et al. Comput Biol Med. 2022 Feb;141:105149. doi: 10.1016/j.compbiomed.2021.105149. Epub 2021 Dec 17. Comput Biol Med. 2022. PMID: 34953359

10

In Silico and In Vitro Studies for Benzimidazole Anthelmintics Repurposing as VEGFR-2 Antagonists: Novel Mebendazole-Loaded Mixed Micelles with Enhanced Dissolution and Anticancer Activity.

Elmaaty AA, Darwish KM, Chrouda A, Boseila AA, Tantawy MA, Elhady SS, Shaik AB, Mustafa M, Al-Karmalawy AA. Elmaaty AA, et al. ACS Omega. 2021 Dec 22;7(1):875-899. doi: 10.1021/acsomega.1c05519. eCollection 2022 Jan 11. ACS Omega. 2021. PMID: 35036753 Free PMC article.

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