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WNK kinases sense molecular crowding and rescue cell volume via phase separation.
Boyd-Shiwarski CR, Shiwarski DJ, Griffiths SE, Beacham RT, Norrell L, Morrison DE, Wang J, Mann J, Tennant W, Anderson EN, Franks J, Calderon M, Connolly KA, Cheema MU, Weaver CJ, Nkashama LJ, Weckerly CC, Querry KE, Pandey UB, Donnelly CJ, Sun D, Rodan AR, Subramanya AR. Boyd-Shiwarski CR, et al. Among authors: mann j. Cell. 2022 Nov 23;185(24):4488-4506.e20. doi: 10.1016/j.cell.2022.09.042. Epub 2022 Oct 31. Cell. 2022. PMID: 36318922 Free PMC article.
RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43.
Mann JR, Gleixner AM, Mauna JC, Gomes E, DeChellis-Marks MR, Needham PG, Copley KE, Hurtle B, Portz B, Pyles NJ, Guo L, Calder CB, Wills ZP, Pandey UB, Kofler JK, Brodsky JL, Thathiah A, Shorter J, Donnelly CJ. Mann JR, et al. Neuron. 2019 Apr 17;102(2):321-338.e8. doi: 10.1016/j.neuron.2019.01.048. Epub 2019 Feb 27. Neuron. 2019. PMID: 30826182 Free PMC article.
NUP62 localizes to ALS/FTLD pathological assemblies and contributes to TDP-43 insolubility.
Gleixner AM, Verdone BM, Otte CG, Anderson EN, Ramesh N, Shapiro OR, Gale JR, Mauna JC, Mann JR, Copley KE, Daley EL, Ortega JA, Cicardi ME, Kiskinis E, Kofler J, Pandey UB, Trotti D, Donnelly CJ. Gleixner AM, et al. Among authors: mann jr. Nat Commun. 2022 Jun 13;13(1):3380. doi: 10.1038/s41467-022-31098-6. Nat Commun. 2022. PMID: 35697676 Free PMC article.
Differences in association between hypoalbuminaemia and mortality among younger versus older patients on haemodialysis.
Sanz-García C, Rodríguez-García M, Górriz-Teruel JL, Martín-Carro B, Floege J, Díaz-López B, Palomo-Antequera C, Sánchez-Alvarez E, Gómez-Alonso C, Fernández-Gómez J, Hevia-Suárez MÁ, Navarro-González JF, Arenas MD, Locatelli F, Zoccali C, Ferreira A, Alonso-Montes C, Cannata-Andía JB, Carrero JJ, Fernández-Martín JL; COSMOS. Sanz-García C, et al. Clin Kidney J. 2024 Nov 13;18(1):sfae339. doi: 10.1093/ckj/sfae339. eCollection 2025 Jan. Clin Kidney J. 2024. PMID: 39781478 Free PMC article.
A Natural Language Processing Pipeline based on the Columbia-Suicide Severity Rating Scale.
Lepow LA, Adekkanattu P, Cusick M, Coon H, Fennessy B, O'Connell S, Pierce C, Rabbany J, Sharma M, Olfson M, Bakian A, Xiao Y, Mullins N, Nadkarni GN, Charney AW, Pathak J, Mann JJ. Lepow LA, et al. Among authors: mann jj. medRxiv [Preprint]. 2024 Dec 20:2024.12.19.24319352. doi: 10.1101/2024.12.19.24319352. medRxiv. 2024. PMID: 39763535 Free PMC article. Preprint.
Small molecule APOL1 inhibitors as a precision medicine approach for APOL1-mediated kidney disease.
Zimmerman B, Dakin LA, Fortier A, Nanou E, Blasio A, Mann J, Miller H, Fletcher M, Wang T, Nanthakumar S, McCarthy G, Matar C, Matsye P, Wang G, Snyder P, Daniel K, Swamy H, Sullivan K, Bright F, Powers A, Gagnon KJ, Lu F, Paula S, Khare-Pandit S, Henry L, Hamel M, Denis F, Nicolas O, Hariparsad N, Kumar S, Proctor J, Senter T, Furey B, Bunnage ME. Zimmerman B, et al. Among authors: mann j. Nat Commun. 2025 Jan 2;16(1):167. doi: 10.1038/s41467-024-55408-2. Nat Commun. 2025. PMID: 39747090 Free PMC article.
4,038 results