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MGAT2 inhibitor decreases liver fibrosis and inflammation in murine NASH models and reduces body weight in human adults with obesity.
Cheng D, Zinker BA, Luo Y, Shipkova P, De Oliveira CH, Krishna G, Brown EA, Boehm SL, Tirucherai GS, Gu H, Ma Z, Chu CH, Onorato JM, Kopcho LM, Ammar R, Smith J, Devasthale P, Lawrence RM, Stryker SA, Dierks EA, Azzara AV, Carayannopoulos L, Charles ED, Lentz KA, Gordon DA. Cheng D, et al. Among authors: krishna g. Cell Metab. 2022 Nov 1;34(11):1732-1748.e5. doi: 10.1016/j.cmet.2022.10.007. Cell Metab. 2022. PMID: 36323235 Free article.
Discovery of 12 (BMS-986172) as a Highly Potent MGAT2 Inhibitor that Achieved Targeted Efficacious Exposures at a Low Human Dose for the Treatment of Metabolic Disorders.
Meng W, Brigance R, Mignone J, Negash L, Zhao G, Ahmad S, Wang W, Moore F, Ye XY, Sun JH, Mathur A, Li YX, Azzara A, Ma Z, Chu CH, Cullen MJ, Rooney S, Harvey S, Kopcho L, Abell L, O'Malley K, Keim W, Dierks EA, Chang S, Foster KA, Harden D, Dabros M, Goti V, De Oliveira C, Krishna G, Pelleymounter MA, Whaley J, Robl JA, Cheng D, Devasthale P. Meng W, et al. Among authors: krishna g. J Med Chem. 2023 Sep 28;66(18):13135-13147. doi: 10.1021/acs.jmedchem.3c01147. Epub 2023 Sep 19. J Med Chem. 2023. PMID: 37724542
Do smoking bans work?
Howard S, Krishna G. Howard S, et al. Among authors: krishna g. BMJ. 2025 Jan 9;388:q2759. doi: 10.1136/bmj.q2759. BMJ. 2025. PMID: 39788606 No abstract available.
Electroceuticals: Unlocking the promise of therapies.
Mishra I, Chaudhary K, Sharma V, Krishna G, Mishra R. Mishra I, et al. Among authors: krishna g. Daru. 2024 Dec 19;33(1):7. doi: 10.1007/s40199-024-00549-4. Daru. 2024. PMID: 39694935 Review.
Tropical eosinophilia: Case series on varying presentations.
Krishna G, Manuel SM, Ananthakrishnan VM. Krishna G, et al. J Family Med Prim Care. 2024 Oct;13(10):4727-4729. doi: 10.4103/jfmpc.jfmpc_1826_23. Epub 2024 Oct 18. J Family Med Prim Care. 2024. PMID: 39629372 Free PMC article.
652 results