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Page 1
A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients.
Pita-Juarez Y, Karagkouni D, Kalavros N, Melms JC, Niezen S, Delorey TM, Essene AL, Brook OR, Pant D, Skelton-Badlani D, Naderi P, Huang P, Pan L, Hether T, Andrews TS, Ziegler CGK, Reeves J, Myloserdnyy A, Chen R, Nam A, Phelan S, Liang Y, Amin AD, Biermann J, Hibshoosh H, Veregge M, Kramer Z, Jacobs C, Yalcin Y, Phillips D, Slyper M, Subramanian A, Ashenberg O, Bloom-Ackermann Z, Tran VM, Gomez J, Sturm A, Zhang S, Fleming SJ, Warren S, Beechem J, Hung D, Babadi M, Padera RF Jr, MacParland SA, Bader GD, Imad N, Solomon IH, Miller E, Riedel S, Porter CBM, Villani AC, Tsai LT, Hide W, Szabo G, Hecht J, Rozenblatt-Rosen O, Shalek AK, Izar B, Regev A, Popov Y, Jiang ZG, Vlachos IS. Pita-Juarez Y, et al. Among authors: hide w. bioRxiv [Preprint]. 2022 Oct 28:2022.10.27.514070. doi: 10.1101/2022.10.27.514070. bioRxiv. 2022. PMID: 36324805 Free PMC article. Preprint.
Integrative pathway analysis across humans and 3D cellular models identifies the p38 MAPK-MK2 axis as a therapeutic target for Alzheimer's disease.
Naderi Yeganeh P, Kwak SS, Jorfi M, Koler K, Kalatturu T, von Maydell D, Liu Z, Guo K, Choi Y, Park J, Abarca N, Bakiasi G, Cetinbas M, Sadreyev R, Griciuc A, Quinti L, Choi SH, Xia W, Tanzi RE, Hide W, Kim DY. Naderi Yeganeh P, et al. Among authors: hide w. Neuron. 2024 Nov 25:S0896-6273(24)00800-6. doi: 10.1016/j.neuron.2024.10.029. Online ahead of print. Neuron. 2024. PMID: 39610246
Unexpected frequency of the pathogenic AR CAG repeat expansion in the general population.
Zanovello M, Ibáñez K, Brown AL, Sivakumar P, Bombaci A, Santos L, van Vugt JJFA, Narzisi G, Karra R, Scholz SW, Ding J, Gibbs JR, Chiò A, Dalgard C, Weisburd B; American Genome Center (TAGC) consortium, Genomics England Research Consortium, Project MinE ALS Sequencing Consortium, The NYGC ALS Consortium; Hanna MG, Greensmith L, Phatnani H, Veldink JH, Traynor BJ, Polke J, Houlden H, Fratta P, Tucci A. Zanovello M, et al. Brain. 2023 Jul 3;146(7):2723-2729. doi: 10.1093/brain/awad050. Brain. 2023. PMID: 36797998 Free PMC article.
A comparison between similarity matrices for principal component analysis to assess population stratification in sequenced genetic data sets.
Lee S, Hahn G, Hecker J, Lutz SM, Mullin K; Alzheimer’s Disease Neuroimaging Initiative (ADNI); Hide W, Bertram L, DeMeo DL, Tanzi RE, Lange C, Prokopenko D. Lee S, et al. Among authors: hide w. Brief Bioinform. 2023 Jan 19;24(1):bbac611. doi: 10.1093/bib/bbac611. Brief Bioinform. 2023. PMID: 36585781 Free PMC article.
Most Pathways Can Be Related to the Pathogenesis of Alzheimer's Disease.
Morgan SL, Naderi P, Koler K, Pita-Juarez Y, Prokopenko D, Vlachos IS, Tanzi RE, Bertram L, Hide WA. Morgan SL, et al. Among authors: hide wa. Front Aging Neurosci. 2022 Jun 24;14:846902. doi: 10.3389/fnagi.2022.846902. eCollection 2022. Front Aging Neurosci. 2022. PMID: 35813951 Free PMC article.
Region-based analysis of rare genomic variants in whole-genome sequencing datasets reveal two novel Alzheimer's disease-associated genes: DTNB and DLG2.
Prokopenko D, Lee S, Hecker J, Mullin K, Morgan S, Katsumata Y; Alzheimer’s Disease Neuroimaging Initiative (ADNI); Weiner MW, Fardo DW, Laird N, Bertram L, Hide W, Lange C, Tanzi RE. Prokopenko D, et al. Among authors: hide w. Mol Psychiatry. 2022 Apr;27(4):1963-1969. doi: 10.1038/s41380-022-01475-0. Epub 2022 Mar 4. Mol Psychiatry. 2022. PMID: 35246634 Free PMC article.
Author Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network.
Grapotte M, Saraswat M, Bessière C, Menichelli C, Ramilowski JA, Severin J, Hayashizaki Y, Itoh M, Tagami M, Murata M, Kojima-Ishiyama M, Noma S, Noguchi S, Kasukawa T, Hasegawa A, Suzuki H, Nishiyori-Sueki H, Frith MC; FANTOM consortium; Chatelain C, Carninci P, de Hoon MJL, Wasserman WW, Bréhélin L, Lecellier CH. Grapotte M, et al. Nat Commun. 2022 Mar 1;13(1):1200. doi: 10.1038/s41467-022-28758-y. Nat Commun. 2022. PMID: 35232988 Free PMC article. No abstract available.
171 results