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SARS-CoV-2 infects human brain organoids causing cell death and loss of synapses that can be rescued by treatment with Sofosbuvir.
Mesci P, de Souza JS, Martin-Sancho L, Macia A, Saleh A, Yin X, Snethlage C, Adams JW, Avansini SH, Herai RH, Almenar-Queralt A, Pu Y, Szeto RA, Goldberg G, Bruck PT, Papes F, Chanda SK, Muotri AR. Mesci P, et al. Among authors: almenar queralt a. PLoS Biol. 2022 Nov 3;20(11):e3001845. doi: 10.1371/journal.pbio.3001845. eCollection 2022 Nov. PLoS Biol. 2022. PMID: 36327326 Free PMC article.
Amyloidogenic Processing of Amyloid Precursor Protein Drives Stretch-Induced Disruption of Axonal Transport in hiPSC-Derived Neurons.
Chaves RS, Tran M, Holder AR, Balcer AM, Dickey AM, Roberts EA, Bober BG, Gutierrez E, Head BP, Groisman A, Goldstein LSB, Almenar-Queralt A, Shah SB. Chaves RS, et al. Among authors: almenar queralt a. J Neurosci. 2021 Dec 8;41(49):10034-10053. doi: 10.1523/JNEUROSCI.2553-20.2021. Epub 2021 Oct 18. J Neurosci. 2021. PMID: 34663629 Free PMC article.
Chromatin establishes an immature version of neuronal protocadherin selection during the naive-to-primed conversion of pluripotent stem cells.
Almenar-Queralt A, Merkurjev D, Kim HS, Navarro M, Ma Q, Chaves RS, Allegue C, Driscoll SP, Chen AG, Kohlnhofer B, Fong LK, Woodruff G, Mackintosh C, Bohaciakova D, Hruska-Plochan M, Tadokoro T, Young JE, El Hajj N, Dittrich M, Marsala M, Goldstein LSB, Garcia-Bassets I. Almenar-Queralt A, et al. Nat Genet. 2019 Dec;51(12):1691-1701. doi: 10.1038/s41588-019-0526-4. Epub 2019 Nov 18. Nat Genet. 2019. PMID: 31740836 Free PMC article.
23 results