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Association of High Polygenic Risk With Visual Field Worsening Despite Treatment in Early Primary Open-Angle Glaucoma.
Siggs OM, Qassim A, Han X, Marshall HN, Mullany S, He W, Souzeau E, Galanopoulos A, Agar A, Landers J, Casson RJ, Hewitt AW, Healey PR, Graham SL, MacGregor S, Craig JE. Siggs OM, et al. Among authors: he w. JAMA Ophthalmol. 2022 Nov 10;141(1):73-7. doi: 10.1001/jamaophthalmol.2022.4688. Online ahead of print. JAMA Ophthalmol. 2022. PMID: 36355370 Free PMC article.
High Polygenic Risk Is Associated with Earlier Initiation and Escalation of Treatment in Early Primary Open-Angle Glaucoma.
Marshall HN, Mullany S, Han X, Qassim A, He W, Hassall MM, Schmidt J, Thomson D, Nguyen TT, Berry EC, Knight LSW, Hollitt GL, Ridge B, Schulz A, Mills RA, Healey PR, Agar A, Galanopoulos A, Landers J, Graham SL, Hewitt AW, Casson RJ, MacGregor S, Siggs OM, Craig JE. Marshall HN, et al. Among authors: he w. Ophthalmology. 2023 Aug;130(8):830-836. doi: 10.1016/j.ophtha.2023.03.028. Epub 2023 Apr 10. Ophthalmology. 2023. PMID: 37044160
Disentangling the genetic overlap and causal relationships between primary open-angle glaucoma, brain morphology and four major neurodegenerative disorders.
Diaz-Torres S, He W, Thorp J, Seddighi S, Mullany S; IGGC International Glaucoma Genetics Consortium; Hammond CJ, Hysi PG, Pasquale LR, Khawaja AP, Hewitt AW, Craig JE, Mackey DA, Wiggs JL, van Duijn C, Lupton MK, Ong JS, MacGregor S, Gharahkhani P. Diaz-Torres S, et al. Among authors: he w. EBioMedicine. 2023 Jun;92:104615. doi: 10.1016/j.ebiom.2023.104615. Epub 2023 May 16. EBioMedicine. 2023. PMID: 37201334 Free PMC article.
Study profile: the Genetics of Glaucoma Study.
Gharahkhani P, He W, Diaz Torres S, Wu Y, Ingold N, Yu R, Seviiri M, Ong JS, Law MH, Craig JE, Mackey DA, Hewitt AW, MacGregor S. Gharahkhani P, et al. Among authors: he w. BMJ Open. 2023 Aug 3;13(8):e068811. doi: 10.1136/bmjopen-2022-068811. BMJ Open. 2023. PMID: 37536973 Free PMC article.
WITHDRAWN: Genome-wide risk prediction of primary open-angle glaucoma across multiple ancestries.
Gharahkhani P, He W, Han X, Ong JS, Rentería ME, Wiggs JL, Khawaja AP, Trzaskowski M, Mackey DA, Craig JE, Hewitt AW; IGGC International Glaucoma Genetics Consortium; MacGregor S, Wu Y. Gharahkhani P, et al. Among authors: he w. medRxiv [Preprint]. 2023 Nov 30:2023.11.08.23298255. doi: 10.1101/2023.11.08.23298255. medRxiv. 2023. PMID: 37986775 Free PMC article. Preprint.
Polygenic Risk Scores and Genetically Complex Eye Disease.
Le NQ, He W, MacGregor S. Le NQ, et al. Among authors: he w. Annu Rev Vis Sci. 2024 Sep;10(1):403-423. doi: 10.1146/annurev-vision-102122-103958. Epub 2024 Sep 2. Annu Rev Vis Sci. 2024. PMID: 38648289 Free article. Review.
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