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Page 1
Kisspeptin modulates sexual and emotional brain processing in humans.
Comninos AN, Wall MB, Demetriou L, Shah AJ, Clarke SA, Narayanaswamy S, Nesbitt A, Izzi-Engbeaya C, Prague JK, Abbara A, Ratnasabapathy R, Salem V, Nijher GM, Jayasena CN, Tanner M, Bassett P, Mehta A, Rabiner EA, Hönigsperger C, Silva MR, Brandtzaeg OK, Lundanes E, Wilson SR, Brown RC, Thomas SA, Bloom SR, Dhillo WS. Comninos AN, et al. Among authors: clarke sa. J Clin Invest. 2017 Feb 1;127(2):709-719. doi: 10.1172/JCI89519. Epub 2017 Jan 23. J Clin Invest. 2017. PMID: 28112678 Free PMC article. Clinical Trial.
Neurokinin 3 receptor antagonism as a novel treatment for menopausal hot flushes: a phase 2, randomised, double-blind, placebo-controlled trial.
Prague JK, Roberts RE, Comninos AN, Clarke S, Jayasena CN, Nash Z, Doyle C, Papadopoulou DA, Bloom SR, Mohideen P, Panay N, Hunter MS, Veldhuis JD, Webber LC, Huson L, Dhillo WS. Prague JK, et al. Lancet. 2017 May 6;389(10081):1809-1820. doi: 10.1016/S0140-6736(17)30823-1. Epub 2017 Apr 3. Lancet. 2017. PMID: 28385352 Free PMC article. Clinical Trial.
Hypothalamic Response to Kisspeptin-54 and Pituitary Response to Gonadotropin-Releasing Hormone Are Preserved in Healthy Older Men.
Abbara A, Narayanaswamy S, Izzi-Engbeaya C, Comninos AN, Clarke SA, Malik Z, Papadopoulou D, Clobentz A, Sarang Z, Bassett P, Jayasena CN, Dhillo WS. Abbara A, et al. Among authors: clarke sa. Neuroendocrinology. 2018;106(4):401-410. doi: 10.1159/000488452. Epub 2018 Mar 15. Neuroendocrinology. 2018. PMID: 29544222 Free PMC article.
Modulations of human resting brain connectivity by kisspeptin enhance sexual and emotional functions.
Comninos AN, Demetriou L, Wall MB, Shah AJ, Clarke SA, Narayanaswamy S, Nesbitt A, Izzi-Engbeaya C, Prague JK, Abbara A, Ratnasabapathy R, Yang L, Salem V, Nijher GM, Jayasena CN, Tanner M, Bassett P, Mehta A, McGonigle J, Rabiner EA, Bloom SR, Dhillo WS. Comninos AN, et al. Among authors: clarke sa. JCI Insight. 2018 Oct 18;3(20):e121958. doi: 10.1172/jci.insight.121958. JCI Insight. 2018. PMID: 30333302 Free PMC article. Clinical Trial.
Kisspeptin receptor agonist has therapeutic potential for female reproductive disorders.
Abbara A, Eng PC, Phylactou M, Clarke SA, Richardson R, Sykes CM, Phumsatitpong C, Mills E, Modi M, Izzi-Engbeaya C, Papadopoulou D, Purugganan K, Jayasena CN, Webber L, Salim R, Owen B, Bech P, Comninos AN, McArdle CA, Voliotis M, Tsaneva-Atanasova K, Moenter S, Hanyaloglu A, Dhillo WS. Abbara A, et al. Among authors: clarke sa. J Clin Invest. 2020 Dec 1;130(12):6739-6753. doi: 10.1172/JCI139681. J Clin Invest. 2020. PMID: 33196464 Free PMC article. Clinical Trial.
Kisspeptin-54 Accurately Identifies Hypothalamic Gonadotropin-Releasing Hormone Neuronal Dysfunction in Men with Congenital Hypogonadotropic Hypogonadism.
Abbara A, Eng PC, Phylactou M, Clarke SA, Mills E, Chia G, Yang L, Izzi-Engbeaya C, Smith N, Jayasena CN, Comninos AN, Anand-Ivell R, Rademaker J, Xu C, Quinton R, Pitteloud N, Dhillo WS. Abbara A, et al. Among authors: clarke sa. Neuroendocrinology. 2021;111(12):1176-1186. doi: 10.1159/000513248. Epub 2020 Nov 23. Neuroendocrinology. 2021. PMID: 33227799
159 results