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CNS Pericytes Modulate Local T Cell Infiltration in EAE.
Koch K, Lindner M, Fleck AK, Liebmann M, Eschborn M, Zondler L, Diéguez-Hurtado R, Adams RH, Meyer Zu Hörste G, Zarbock A, Kuhlmann T, Wiendl H, Klotz L. Koch K, et al. Among authors: liebmann m. Int J Mol Sci. 2022 Oct 28;23(21):13081. doi: 10.3390/ijms232113081. Int J Mol Sci. 2022. PMID: 36361868 Free PMC article.
The farnesoid-X-receptor in myeloid cells controls CNS autoimmunity in an IL-10-dependent fashion.
Hucke S, Herold M, Liebmann M, Freise N, Lindner M, Fleck AK, Zenker S, Thiebes S, Fernandez-Orth J, Buck D, Luessi F, Meuth SG, Zipp F, Hemmer B, Engel DR, Roth J, Kuhlmann T, Wiendl H, Klotz L. Hucke S, et al. Among authors: liebmann m. Acta Neuropathol. 2016 Sep;132(3):413-31. doi: 10.1007/s00401-016-1593-6. Epub 2016 Jul 6. Acta Neuropathol. 2016. PMID: 27383204
Activation of FXR pathway does not alter glial cell function.
Albrecht S, Fleck AK, Kirchberg I, Hucke S, Liebmann M, Klotz L, Kuhlmann T. Albrecht S, et al. Among authors: liebmann m. J Neuroinflammation. 2017 Mar 28;14(1):66. doi: 10.1186/s12974-017-0833-6. J Neuroinflammation. 2017. PMID: 28351411 Free PMC article.
Nur77 serves as a molecular brake of the metabolic switch during T cell activation to restrict autoimmunity.
Liebmann M, Hucke S, Koch K, Eschborn M, Ghelman J, Chasan AI, Glander S, Schädlich M, Kuhlencord M, Daber NM, Eveslage M, Beyer M, Dietrich M, Albrecht P, Stoll M, Busch KB, Wiendl H, Roth J, Kuhlmann T, Klotz L. Liebmann M, et al. Proc Natl Acad Sci U S A. 2018 Aug 21;115(34):E8017-E8026. doi: 10.1073/pnas.1721049115. Epub 2018 Aug 2. Proc Natl Acad Sci U S A. 2018. PMID: 30072431 Free PMC article.
Dietary salt promotes ischemic brain injury and is associated with parenchymal migrasome formation.
Schmidt-Pogoda A, Strecker JK, Liebmann M, Massoth C, Beuker C, Hansen U, König S, Albrecht S, Bock S, Breuer J, Sommer C, Schwab N, Wiendl H, Klotz L, Minnerup J. Schmidt-Pogoda A, et al. Among authors: liebmann m. PLoS One. 2018 Dec 27;13(12):e0209871. doi: 10.1371/journal.pone.0209871. eCollection 2018. PLoS One. 2018. PMID: 30589884 Free PMC article.
Teriflunomide treatment for multiple sclerosis modulates T cell mitochondrial respiration with affinity-dependent effects.
Klotz L, Eschborn M, Lindner M, Liebmann M, Herold M, Janoschka C, Torres Garrido B, Schulte-Mecklenbeck A, Gross CC, Breuer J, Hundehege P, Posevitz V, Pignolet B, Nebel G, Glander S, Freise N, Austermann J, Wirth T, Campbell GR, Schneider-Hohendorf T, Eveslage M, Brassat D, Schwab N, Loser K, Roth J, Busch KB, Stoll M, Mahad DJ, Meuth SG, Turner T, Bar-Or A, Wiendl H. Klotz L, et al. Among authors: liebmann m. Sci Transl Med. 2019 May 1;11(490):eaao5563. doi: 10.1126/scitranslmed.aao5563. Sci Transl Med. 2019. PMID: 31043571 Clinical Trial.
Dietary conjugated linoleic acid links reduced intestinal inflammation to amelioration of CNS autoimmunity.
Fleck AK, Hucke S, Teipel F, Eschborn M, Janoschka C, Liebmann M, Wami H, Korn L, Pickert G, Hartwig M, Wirth T, Herold M, Koch K, Falk-Paulsen M, Dobrindt U, Kovac S, Gross CC, Rosenstiel P, Trautmann M, Wiendl H, Schuppan D, Kuhlmann T, Klotz L. Fleck AK, et al. Among authors: liebmann m. Brain. 2021 May 7;144(4):1152-1166. doi: 10.1093/brain/awab040. Brain. 2021. PMID: 33899089 Free PMC article. Clinical Trial.
K2P18.1 translates T cell receptor signals into thymic regulatory T cell development.
Ruck T, Bock S, Pfeuffer S, Schroeter CB, Cengiz D, Marciniak P, Lindner M, Herrmann A, Liebmann M, Kovac S, Gola L, Rolfes L, Pawlitzki M, Opel N, Hahn T, Dannlowski U, Pap T, Luessi F, Schreiber JA, Wünsch B, Kuhlmann T, Seebohm G, Tackenberg B, Seja P, Döring F, Wischmeyer E, Chasan AI, Roth J, Klotz L, Meyer Zu Hörste G, Wiendl H, Marschall T, Floess S, Huehn J, Budde T, Bopp T, Bittner S, Meuth SG. Ruck T, et al. Among authors: liebmann m. Cell Res. 2022 Jan;32(1):72-88. doi: 10.1038/s41422-021-00580-z. Epub 2021 Oct 26. Cell Res. 2022. PMID: 34702947 Free PMC article.
Dimethyl fumarate treatment restrains the antioxidative capacity of T cells to control autoimmunity.
Liebmann M, Korn L, Janoschka C, Albrecht S, Lauks S, Herrmann AM, Schulte-Mecklenbeck A, Schwab N, Schneider-Hohendorf T, Eveslage M, Wildemann B, Luessi F, Schmidt S, Diebold M, Bittner S, Gross CC, Kovac S, Zipp F, Derfuss T, Kuhlmann T, König S, Meuth SG, Wiendl H, Klotz L. Liebmann M, et al. Brain. 2021 Nov 29;144(10):3126-3141. doi: 10.1093/brain/awab307. Brain. 2021. PMID: 34849598 Free PMC article. Clinical Trial.
67 results