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Uncloaking cell-impermeant gold nanorods via tumor microenvironmental cathepsin B facilitates cancer cell penetration and potent radiosensitization.
Raghuram S, Mackeyev Y, Symons J, Zahra Y, Gonzalez V, Mahadevan KK, Requejo KI, Liopo A, Derry P, Zubarev E, Sahin O, Byung-Kyu Kim J, Singh PK, Cho SH, Krishnan S. Raghuram S, et al. Among authors: zahra y. Biomaterials. 2022 Dec;291:121887. doi: 10.1016/j.biomaterials.2022.121887. Epub 2022 Nov 2. Biomaterials. 2022. PMID: 36368139 Free PMC article.
Pancreatic tumor microenvironmental acidosis and hypoxia transform gold nanorods into cell-penetrant particles for potent radiosensitization.
Rauta PR, Mackeyev Y, Sanders K, Kim JBK, Gonzalez VV, Zahra Y, Shohayeb MA, Abousaida B, Vijay GV, Tezcan O, Derry P, Liopo AV, Zubarev ER, Carter R, Singh P, Krishnan S. Rauta PR, et al. Among authors: zahra y. Sci Adv. 2022 Nov 11;8(45):eabm9729. doi: 10.1126/sciadv.abm9729. Epub 2022 Nov 11. Sci Adv. 2022. PMID: 36367938 Free PMC article.