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Towards increased accuracy and reproducibility in SARS-CoV-2 next generation sequence analysis for public health surveillance.
Connor R, Yarmosh DA, Maier W, Shakya M, Martin R, Bradford R, Brister JR, Chain PS, Copeland CA, di Iulio J, Hu B, Ebert P, Gunti J, Jin Y, Katz KS, Kochergin A, LaRosa T, Li J, Li PE, Lo CC, Rashid S, Maiorova ES, Xiao C, Zalunin V, Pruitt KD. Connor R, et al. Among authors: maier w. bioRxiv [Preprint]. 2022 Nov 3:2022.11.03.515010. doi: 10.1101/2022.11.03.515010. bioRxiv. 2022. Update in: Viruses. 2024 Mar 11;16(3):430. doi: 10.3390/v16030430 PMID: 36380755 Free PMC article. Updated. Preprint.
Freely accessible ready to use global infrastructure for SARS-CoV-2 monitoring.
Maier W, Bray S, van den Beek M, Bouvier D, Coraor N, Miladi M, Singh B, De Argila JR, Baker D, Roach N, Gladman S, Coppens F, Martin DP, Lonie A, Grüning B, Kosakovsky Pond SL, Nekrutenko A. Maier W, et al. bioRxiv [Preprint]. 2021 Mar 25:2021.03.25.437046. doi: 10.1101/2021.03.25.437046. bioRxiv. 2021. Update in: Nat Biotechnol. 2021 Oct;39(10):1178-1179. doi: 10.1038/s41587-021-01069-1 PMID: 33791701 Free PMC article. Updated. Preprint.
Selection analysis identifies unusual clustered mutational changes in Omicron lineage BA.1 that likely impact Spike function.
Martin DP, Lytras S, Lucaci AG, Maier W, Grüning B, Shank SD, Weaver S, MacLean OA, Orton RJ, Lemey P, Boni MF, Tegally H, Harkins G, Scheepers C, Bhiman JN, Everatt J, Amoako DG, San JE, Giandhari J, Sigal A; NGS-SA; Williamson C, Hsiao NY, von Gottberg A, De Klerk A, Shafer RW, Robertson DL, Wilkinson RJ, Sewell BT, Lessells R, Nekrutenko A, Greaney AJ, Starr TN, Bloom JD, Murrell B, Wilkinson E, Gupta RK, de Oliveira T, Kosakovsky Pond SL. Martin DP, et al. Among authors: maier w. bioRxiv [Preprint]. 2022 Jan 18:2022.01.14.476382. doi: 10.1101/2022.01.14.476382. bioRxiv. 2022. Update in: Mol Biol Evol. 2022 Apr 11;39(4):msac061. doi: 10.1093/molbev/msac061 PMID: 35075456 Free PMC article. Updated. Preprint.
Mobilisation and analyses of publicly available SARS-CoV-2 data for pandemic responses.
Rahman N, O'Cathail C, Zyoud A, Sokolov A, Oude Munnink B, Grüning B, Cummins C, Amid C, Nieuwenhuijse DF, Visontai D, Yuan DY, Gupta D, Prasad DK, Gulyás GM, Rinck G, McKinnon J, Rajan J, Knaggs J, Skiby JE, Stéger J, Szarvas J, Gueye K, Papp K, Hoek M, Kumar M, Ventouratou MA, Bouquieaux MC, Koliba M, Mansurova M, Haseeb M, Worp N, Harrison PW, Leinonen R, Thorne R, Selvakumar S, Hunt S, Venkataraman S, Jayathilaka S, Cezard T, Maier W, Waheed Z, Iqbal Z, Aarestrup FM, Csabai I, Koopmans M, Burdett T, Cochrane G. Rahman N, et al. Among authors: maier w. Microb Genom. 2024 Feb;10(2):001188. doi: 10.1099/mgen.0.001188. Microb Genom. 2024. PMID: 38358325 Free PMC article.
Genomics yields biological and phenotypic insights into bipolar disorder.
O'Connell KS, Koromina M, van der Veen T, Boltz T, David FS, Yang JMK, Lin KH, Wang X, Coleman JRI, Mitchell BL, McGrouther CC, Rangan AV, Lind PA, Koch E, Harder A, Parker N, Bendl J, Adorjan K, Agerbo E, Albani D, Alemany S, Alliey-Rodriguez N, Als TD, Andlauer TFM, Antoniou A, Ask H, Bass N, Bauer M, Beins EC, Bigdeli TB, Pedersen CB, Boks MP, Børte S, Bosch R, Brum M, Brumpton BM, Brunkhorst-Kanaan N, Budde M, Bybjerg-Grauholm J, Byerley W, Cabana-Domínguez J, Cairns MJ, Carpiniello B, Casas M, Cervantes P, Chatzinakos C, Chen HC, Clarence T, Clarke TK, Claus I, Coombes B, Corfield EC, Cruceanu C, Cuellar-Barboza A, Czerski PM, Dafnas K, Dale AM, Dalkner N, Degenhardt F, DePaulo JR, Djurovic S, Drange OK, Escott-Price V, Fanous AH, Fellendorf FT, Ferrier IN, Forty L, Frank J, Frei O, Freimer NB, Fullard JF, Garnham J, Gizer IR, Gordon SD, Gordon-Smith K, Greenwood TA, Grove J, Guzman-Parra J, Ha TH, Hahn T, Haraldsson M, Hautzinger M, Havdahl A, Heilbronner U, Hellgren D, Herms S, Hickie IB, Hoffmann P, Holmans PA, Huang MC, Ikeda M, Jamain S, Johnson JS, Jonsson L, Kalman JL, Kamatani Y, Kennedy JL, Kim E, Kim J, Kittel-Schneider S, Knowles JA, Kogevinas M, Kranz TM, Krebs K,… See abstract for full author list ➔ O'Connell KS, et al. Among authors: maier w. Nature. 2025 Jan 22. doi: 10.1038/s41586-024-08468-9. Online ahead of print. Nature. 2025. PMID: 39843750
Trans-ancestry genome-wide study of depression identifies 697 associations implicating cell types and pharmacotherapies.
Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. Electronic address: andrew.mcintosh@ed.ac.uk; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. Electronic address: andrew.mcintosh@ed.ac.uk, et al. Cell. 2025 Jan 14:S0092-8674(24)01415-6. doi: 10.1016/j.cell.2024.12.002. Online ahead of print. Cell. 2025. PMID: 39814019 Free article.
1,946 results