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Discovery of κ Opioid Receptor (KOR)-Selective d-Tetrapeptides with Improved In Vivo Antinociceptive Effect after Peripheral Administration.
Stefanucci A, Della Valle A, Scioli G, Marinaccio L, Pieretti S, Minosi P, Szucs E, Benyhe S, Masci D, Tanguturi P, Chou K, Barlow D, Houseknecht K, Streicher JM, Mollica A. Stefanucci A, et al. Among authors: streicher jm. ACS Med Chem Lett. 2022 Oct 17;13(11):1707-1714. doi: 10.1021/acsmedchemlett.2c00237. eCollection 2022 Nov 10. ACS Med Chem Lett. 2022. PMID: 36385929 Free PMC article.
Analgesic Properties of Opioid/NK1 Multitarget Ligands with Distinct in Vitro Profiles in Naive and Chronic Constriction Injury Mice.
Starnowska J, Costante R, Guillemyn K, Popiolek-Barczyk K, Chung NN, Lemieux C, Keresztes A, Van Duppen J, Mollica A, Streicher J, Vanden Broeck J, Schiller PW, Tourwé D, Mika J, Ballet S, Przewlocka B. Starnowska J, et al. ACS Chem Neurosci. 2017 Oct 18;8(10):2315-2324. doi: 10.1021/acschemneuro.7b00226. Epub 2017 Jul 26. ACS Chem Neurosci. 2017. PMID: 28699350 Free PMC article.
Novel Cyclic Biphalin Analogues by Ruthenium-Catalyzed Ring Closing Metathesis: in Vivo and in Vitro Biological Profile.
Stefanucci A, Lei W, Pieretti S, Dimmito MP, Luisi G, Novellino E, Nowakowski M, Koźmiński W, Mirzaie S, Zengin G, Streicher JM, Mollica A. Stefanucci A, et al. Among authors: streicher jm. ACS Med Chem Lett. 2019 Mar 8;10(4):450-456. doi: 10.1021/acsmedchemlett.8b00495. eCollection 2019 Apr 11. ACS Med Chem Lett. 2019. PMID: 30996778 Free PMC article.
Synthesis and Structure-Activity Relationships of 5'-Aryl-14-alkoxypyridomorphinans: Identification of a μ Opioid Receptor Agonist/δ Opioid Receptor Antagonist Ligand with Systemic Antinociceptive Activity and Diminished Opioid Side Effects.
Vekariya RH, Lei W, Ray A, Saini SK, Zhang S, Molnar G, Barlow D, Karlage KL, Bilsky EJ, Houseknecht KL, Largent-Milnes TM, Streicher JM, Ananthan S. Vekariya RH, et al. Among authors: streicher jm. J Med Chem. 2020 Jul 23;63(14):7663-7694. doi: 10.1021/acs.jmedchem.0c00503. Epub 2020 Jun 30. J Med Chem. 2020. PMID: 32530286 Free PMC article.
Synthesis and Pharmacology of a Novel μ-δ Opioid Receptor Heteromer-Selective Agonist Based on the Carfentanyl Template.
Faouzi A, Uprety R, Gomes I, Massaly N, Keresztes AI, Le Rouzic V, Gupta A, Zhang T, Yoon HJ, Ansonoff M, Allaoa A, Pan YX, Pintar J, Morón JA, Streicher JM, Devi LA, Majumdar S. Faouzi A, et al. Among authors: streicher jm. J Med Chem. 2020 Nov 25;63(22):13618-13637. doi: 10.1021/acs.jmedchem.0c00901. Epub 2020 Nov 10. J Med Chem. 2020. PMID: 33170687 Free PMC article.
79 results