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How Carvedilol activates β2-adrenoceptors.
Benkel T, Zimmermann M, Zeiner J, Bravo S, Merten N, Lim VJY, Matthees ESF, Drube J, Miess-Tanneberg E, Malan D, Szpakowska M, Monteleone S, Grimes J, Koszegi Z, Lanoiselée Y, O'Brien S, Pavlaki N, Dobberstein N, Inoue A, Nikolaev V, Calebiro D, Chevigné A, Sasse P, Schulz S, Hoffmann C, Kolb P, Waldhoer M, Simon K, Gomeza J, Kostenis E. Benkel T, et al. Among authors: grimes j. Nat Commun. 2022 Nov 19;13(1):7109. doi: 10.1038/s41467-022-34765-w. Nat Commun. 2022. PMID: 36402762 Free PMC article.
Plasma membrane preassociation drives β-arrestin coupling to receptors and activation.
Grimes J, Koszegi Z, Lanoiselée Y, Miljus T, O'Brien SL, Stepniewski TM, Medel-Lacruz B, Baidya M, Makarova M, Mistry R, Goulding J, Drube J, Hoffmann C, Owen DM, Shukla AK, Selent J, Hill SJ, Calebiro D. Grimes J, et al. Cell. 2023 May 11;186(10):2238-2255.e20. doi: 10.1016/j.cell.2023.04.018. Epub 2023 May 4. Cell. 2023. PMID: 37146613 Free PMC article.
Structural characterization of the full-length Hantaan virus polymerase.
Keown JR, Carrique L, Nilsson-Payant BE, Fodor E, Grimes JM. Keown JR, et al. Among authors: grimes jm. PLoS Pathog. 2024 Dec 9;20(12):e1012781. doi: 10.1371/journal.ppat.1012781. eCollection 2024 Dec. PLoS Pathog. 2024. PMID: 39652621 Free PMC article.
Structure of the RNA-dependent RNA polymerase P2 from the cystovirus φ8.
Latimer-Smith M, Salgado PS, Forsyth I, Makeyev E, Poranen MM, Stuart DI, Grimes JM, El Omari K. Latimer-Smith M, et al. Among authors: grimes jm. Sci Rep. 2024 Oct 9;14(1):23540. doi: 10.1038/s41598-024-75213-7. Sci Rep. 2024. PMID: 39384884 Free PMC article.
646 results