Takahashi Y - Search Results

1

Modulation of cGAS-STING signaling by PPARα in a mouse model of ischemia-induced retinopathy.

Ma X, Wu W, Liang W, Takahashi Y, Cai J, Ma JX. Ma X, et al. Among authors: takahashi y. Proc Natl Acad Sci U S A. 2022 Nov 29;119(48):e2208934119. doi: 10.1073/pnas.2208934119. Epub 2022 Nov 21. Proc Natl Acad Sci U S A. 2022. PMID: 36409895 Free PMC article.

2

RPE65 is the isomerohydrolase in the retinoid visual cycle.

Moiseyev G, Chen Y, Takahashi Y, Wu BX, Ma JX. Moiseyev G, et al. Among authors: takahashi y. Proc Natl Acad Sci U S A. 2005 Aug 30;102(35):12413-8. doi: 10.1073/pnas.0503460102. Epub 2005 Aug 22. Proc Natl Acad Sci U S A. 2005. PMID: 16116091 Free PMC article.

3

Identification of conserved histidines and glutamic acid as key residues for isomerohydrolase activity of RPE65, an enzyme of the visual cycle in the retinal pigment epithelium.

Takahashi Y, Moiseyev G, Chen Y, Ma JX. Takahashi Y, et al. FEBS Lett. 2005 Oct 10;579(24):5414-8. doi: 10.1016/j.febslet.2005.09.002. FEBS Lett. 2005. PMID: 16198348 Free article.

4

RPE65 is an iron(II)-dependent isomerohydrolase in the retinoid visual cycle.

Moiseyev G, Takahashi Y, Chen Y, Gentleman S, Redmond TM, Crouch RK, Ma JX. Moiseyev G, et al. Among authors: takahashi y. J Biol Chem. 2006 Feb 3;281(5):2835-40. doi: 10.1074/jbc.M508903200. Epub 2005 Nov 30. J Biol Chem. 2006. PMID: 16319067 Free article.

5

RPE65 gene delivery restores isomerohydrolase activity and prevents early cone loss in Rpe65-/- mice.

Chen Y, Moiseyev G, Takahashi Y, Ma JX. Chen Y, et al. Among authors: takahashi y. Invest Ophthalmol Vis Sci. 2006 Mar;47(3):1177-84. doi: 10.1167/iovs.05-0965. Invest Ophthalmol Vis Sci. 2006. PMID: 16505056

6

Two point mutations of RPE65 from patients with retinal dystrophies decrease the stability of RPE65 protein and abolish its isomerohydrolase activity.

Takahashi Y, Chen Y, Moiseyev G, Ma JX. Takahashi Y, et al. J Biol Chem. 2006 Aug 4;281(31):21820-21826. doi: 10.1074/jbc.M603725200. Epub 2006 Jun 5. J Biol Chem. 2006. PMID: 16754667 Free article.

7

Impacts of two point mutations of RPE65 from Leber's congenital amaurosis on the stability, subcellular localization and isomerohydrolase activity of RPE65.

Chen Y, Moiseyev G, Takahashi Y, Ma JX. Chen Y, et al. Among authors: takahashi y. FEBS Lett. 2006 Jul 24;580(17):4200-4. doi: 10.1016/j.febslet.2006.06.078. Epub 2006 Jul 5. FEBS Lett. 2006. PMID: 16828753 Free article.

8

The roles of three palmitoylation sites of RPE65 in its membrane association and isomerohydrolase activity.

Takahashi Y, Moiseyev G, Chen Y, Ma JX. Takahashi Y, et al. Invest Ophthalmol Vis Sci. 2006 Dec;47(12):5191-6. doi: 10.1167/iovs.06-0614. Invest Ophthalmol Vis Sci. 2006. PMID: 17122102

9

RPE65 from cone-dominant chicken is a more efficient isomerohydrolase compared with that from rod-dominant species.

Moiseyev G, Takahashi Y, Chen Y, Kim S, Ma JX. Moiseyev G, et al. Among authors: takahashi y. J Biol Chem. 2008 Mar 28;283(13):8110-7. doi: 10.1074/jbc.M703654200. Epub 2008 Jan 23. J Biol Chem. 2008. PMID: 18216020 Free PMC article.

10

Identification of a novel palmitylation site essential for membrane association and isomerohydrolase activity of RPE65.

Takahashi Y, Moiseyev G, Ablonczy Z, Chen Y, Crouch RK, Ma JX. Takahashi Y, et al. J Biol Chem. 2009 Jan 30;284(5):3211-3218. doi: 10.1074/jbc.M807248200. Epub 2008 Dec 1. J Biol Chem. 2009. PMID: 19049981 Free PMC article.

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