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A high-throughput sequencing approach identifies immunotherapeutic targets for bacterial meningitis in neonates.
Pons S, Frapy E, Sereme Y, Gaultier C, Lebreton F, Kropec A, Danilchanka O, Schlemmer L, Schrimpf C, Allain M, Angoulvant F, Lecuyer H, Bonacorsi S, Aschard H, Sokol H, Cywes-Bentley C, Mekalanos JJ, Guillard T, Pier GB, Roux D, Skurnik D. Pons S, et al. Among authors: aschard h. EBioMedicine. 2023 Feb;88:104439. doi: 10.1016/j.ebiom.2023.104439. Epub 2023 Jan 27. EBioMedicine. 2023. PMID: 36709579 Free PMC article.
Integrated analysis of whole blood oxylipin and cytokine responses after bacterial, viral, and T cell stimulation reveals new immune networks.
Villain E, Chanson A, Mainka M, Kampschulte N, Le Faouder P, Bertrand-Michel J, Brandolini-Bulon M, Charbit B, Musvosvi M, Bilek N, Scriba TJ, Quintana-Murci L, Schebb NH, Duffy D, Gladine C; Milieu Interieur Consortium. Villain E, et al. iScience. 2023 Jul 18;26(8):107422. doi: 10.1016/j.isci.2023.107422. eCollection 2023 Aug 18. iScience. 2023. PMID: 37575177 Free PMC article.
Pitfalls in performing genome-wide association studies on ratio traits.
McCaw ZR, Dey R, Somineni H, Amar D, Mukherjee S, Sandor K; insitro Research Team; Karaletsos T, Koller D, Aschard H, Smith GD, MacArthur D, O'Dushlaine C, Soare TW. McCaw ZR, et al. Among authors: aschard h. HGG Adv. 2025 Jan 15:100406. doi: 10.1016/j.xhgg.2025.100406. Online ahead of print. HGG Adv. 2025. PMID: 39818621 Free article.
Refinement of a Published Gene-Physical Activity Interaction Impacting HDL-Cholesterol: Role of Sex and Lipoprotein Subfractions.
Westerman KE, Kilpeläinen TO, Sevilla-Gonzalez M, Connelly MA, Wood AC, Tsai MY, Taylor KD, Rich SS, Rotter JI, Otvos JD, Bentley AR, Mora S, Aschard H, Rao DC, Gu C, Chasman DI, Manning AK; CHARGE Gene‐Lifestyle Interactions Working Group. Westerman KE, et al. Among authors: aschard h. Genet Epidemiol. 2025 Jan;49(1):e22607. doi: 10.1002/gepi.22607. Genet Epidemiol. 2025. PMID: 39764704
Differential stress responsiveness determines intraspecies virulence heterogeneity and host adaptation in Listeria monocytogenes.
Hafner L, Gadin E, Huang L, Frouin A, Laporte F, Gaultier C, Vieira A, Maudet C, Varet H, Moura A, Bracq-Dieye H, Tessaud-Rita N, Maury M, Dazas M, Legendre R, Gastineau P, Tsai YH, Coppée JY, Charlier C, Patin E, Chikhi R, Rocha EPC, Leclercq A, Disson O, Aschard H, Lecuit M. Hafner L, et al. Among authors: aschard h. Nat Microbiol. 2024 Dec;9(12):3345-3361. doi: 10.1038/s41564-024-01859-8. Epub 2024 Nov 22. Nat Microbiol. 2024. PMID: 39578578
A Large-Scale Genome-Wide Gene-Sleep Interaction Study in 732,564 Participants Identifies Lipid Loci Explaining Sleep-Associated Lipid Disturbances.
Noordam R, Wang W, Nagarajan P, Wang H, Brown MR, Bentley AR, Hui Q, Kraja AT, Morrison JL, O'Connel JR, Lee S, Schwander K, Bartz TM, de las Fuentes L, Feitosa MF, Guo X, Hanfei X, Harris SE, Huang Z, Kals M, Lefevre C, Mangino M, Milaneschi Y, van der Most P, Pacheco NL, Palmer ND, Rao V, Rauramaa R, Sun Q, Tabara Y, Vojinovic D, Wang Y, Weiss S, Yang Q, Zhao W, Zhu W, Abu Yusuf Ansari M, Aschard H, Anugu P, Assimes TL, Attia J, Baker LD, Ballantyne C, Bazzano L, Boerwinkle E, Cade B, Chen HH, Chen W, Ida Chen YD, Chen Z, Cho K, De Anda-Duran I, Dimitrov L, Do A, Edwards T, Faquih T, Hingorani A, Fisher-Hoch SP, Gaziano JM, Gharib SA, Giri A, Ghanbari M, Grabe HJ, Graff M, Gu CC, He J, Heikkinen S, Hixson J, Ho YL, Hood MM, Houghton SC, Karvonen-Gutierrez CA, Kawaguchi T, Kilpeläinen TO, Komulainen P, Lin HJ, Linchangco GV, Luik AI, Ma J, Meigs JB, McCormick JB, Menni C, Nolte IM, Norris JM, Petty LE, Polikowsky HG, Raffield LM, Rich SS, Riha RL, Russ TC, Ruiz-Narvaez EA, Sitlani CM, Smith JA, Snieder H, Sofer T, Shen B, Tang J, Taylor KD, Teder-Laving M, Triatin R, Tsai MY, Völzke H, Westerman KE, Xia R, Yao J, Young KL, Zhang R, Zonderman AB, Zhu X, Below JE, Cox SR, Ev… See abstract for full author list ➔ Noordam R, et al. Among authors: aschard h. medRxiv [Preprint]. 2024 Sep 4:2024.09.02.24312466. doi: 10.1101/2024.09.02.24312466. medRxiv. 2024. PMID: 39281768 Free PMC article. Preprint.
Multitrait Analysis to Decipher the Intertwined Genetic Architecture of Neuroanatomical Phenotypes and Psychiatric Disorders.
Auvergne A, Traut N, Henches L, Troubat L, Frouin A, Boetto C, Kazem S, Julienne H, Toro R, Aschard H. Auvergne A, et al. Among authors: aschard h. Biol Psychiatry Cogn Neurosci Neuroimaging. 2024 Sep 10:S2451-9022(24)00266-0. doi: 10.1016/j.bpsc.2024.08.018. Online ahead of print. Biol Psychiatry Cogn Neurosci Neuroimaging. 2024. PMID: 39260564 Free article.
A Large-Scale Genome-Wide Study of Gene-Sleep Duration Interactions for Blood Pressure in 811,405 Individuals from Diverse Populations.
Wang H, Nagarajan P, Winkler T, Bentley A, Miller C, Kraja A, Schwander K, Lee S, Wang W, Brown M, Morrison J, Giri A, O'Connell J, Bartz T, de las Fuentes L, Gudmundsdottir V, Guo X, Harris S, Huang Z, Kals M, Kho M, Lefevre C, Luan J, Lyytikäinen LP, Mangino M, Milaneschi Y, Palmer N, Rao V, Rauramaa R, Shen B, Stadler S, Sun Q, Tang J, Thériault S, van der Graaf A, van der Most P, Wang Y, Weiss S, Westerman K, Yang Q, Yasuharu T, Zhao W, Zhu W, Altschul D, Ansari MAY, Anugu P, Argoty-Pantoja A, Arzt M, Aschard H, Attia J, Bazzano L, Breyer M, Brody J, Cade B, Chen HH, Chen YI, Chen Z, de Vries P, Dimitrov L, Do A, Du J, Dupont C, Edwards T, Evans M, Faquih T, Felix S, Fisher-Hoch S, Floyd J, Graff M, Charles Gu C, Gu D, Hairston K, Hanley A, Heid I, Heikkinen S, Highland H, Hood M, Kähönen M, Karvonen-Gutierrez C, Kawaguchi T, Kazuya S, Tanika K, Komulainen P, Levy D, Lin H, Liu P, Marques-Vidal P, McCormick J, Mei H, Meigs J, Menni C, Nam K, Nolte I, Pacheco N, Petty L, Polikowsky H, Province M, Psaty B, Raffield L, Raitakari O, Rich S, Riha R, Risch L, Risch M, Ruiz-Narvaez E, Scott R, Sitlani C, Smith J, Sofer T, Teder-Laving M, Völker U, Vollenweider P, Wang G, van D… See abstract for full author list ➔ Wang H, et al. Among authors: aschard h. Res Sq [Preprint]. 2024 Jul 17:rs.3.rs-4163414. doi: 10.21203/rs.3.rs-4163414/v1. Res Sq. 2024. PMID: 39070651 Free PMC article. Preprint.
136 results