Weissman D - Search Results

1

A multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes.

Arevalo CP, Bolton MJ, Le Sage V, Ye N, Furey C, Muramatsu H, Alameh MG, Pardi N, Drapeau EM, Parkhouse K, Garretson T, Morris JS, Moncla LH, Tam YK, Fan SHY, Lakdawala SS, Weissman D, Hensley SE. Arevalo CP, et al. Among authors: weissman d. Science. 2022 Nov 25;378(6622):899-904. doi: 10.1126/science.abm0271. Epub 2022 Nov 24. Science. 2022. PMID: 36423275 Free PMC article.

2

Incorporation of pseudouridine into mRNA yields superior nonimmunogenic vector with increased translational capacity and biological stability.

Karikó K, Muramatsu H, Welsh FA, Ludwig J, Kato H, Akira S, Weissman D. Karikó K, et al. Among authors: weissman d. Mol Ther. 2008 Nov;16(11):1833-40. doi: 10.1038/mt.2008.200. Epub 2008 Sep 16. Mol Ther. 2008. PMID: 18797453 Free PMC article.

3

Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation.

Anderson BR, Muramatsu H, Nallagatla SR, Bevilacqua PC, Sansing LH, Weissman D, Karikó K. Anderson BR, et al. Among authors: weissman d. Nucleic Acids Res. 2010 Sep;38(17):5884-92. doi: 10.1093/nar/gkq347. Epub 2010 May 10. Nucleic Acids Res. 2010. PMID: 20457754 Free PMC article.

4

Nucleoside modifications in RNA limit activation of 2'-5'-oligoadenylate synthetase and increase resistance to cleavage by RNase L.

Anderson BR, Muramatsu H, Jha BK, Silverman RH, Weissman D, Karikó K. Anderson BR, et al. Among authors: weissman d. Nucleic Acids Res. 2011 Nov;39(21):9329-38. doi: 10.1093/nar/gkr586. Epub 2011 Aug 3. Nucleic Acids Res. 2011. PMID: 21813458 Free PMC article.

5

Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA.

Karikó K, Muramatsu H, Ludwig J, Weissman D. Karikó K, et al. Among authors: weissman d. Nucleic Acids Res. 2011 Nov;39(21):e142. doi: 10.1093/nar/gkr695. Epub 2011 Sep 2. Nucleic Acids Res. 2011. PMID: 21890902 Free PMC article.

6

Increased erythropoiesis in mice injected with submicrogram quantities of pseudouridine-containing mRNA encoding erythropoietin.

Karikó K, Muramatsu H, Keller JM, Weissman D. Karikó K, et al. Among authors: weissman d. Mol Ther. 2012 May;20(5):948-53. doi: 10.1038/mt.2012.7. Epub 2012 Feb 14. Mol Ther. 2012. PMID: 22334017 Free PMC article.

7

In vitro transcription of long RNA containing modified nucleosides.

Pardi N, Muramatsu H, Weissman D, Karikó K. Pardi N, et al. Among authors: weissman d. Methods Mol Biol. 2013;969:29-42. doi: 10.1007/978-1-62703-260-5_2. Methods Mol Biol. 2013. PMID: 23296925 Review.

8

HPLC purification of in vitro transcribed long RNA.

Weissman D, Pardi N, Muramatsu H, Karikó K. Weissman D, et al. Methods Mol Biol. 2013;969:43-54. doi: 10.1007/978-1-62703-260-5_3. Methods Mol Biol. 2013. PMID: 23296926

9

Expression kinetics of nucleoside-modified mRNA delivered in lipid nanoparticles to mice by various routes.

Pardi N, Tuyishime S, Muramatsu H, Kariko K, Mui BL, Tam YK, Madden TD, Hope MJ, Weissman D. Pardi N, et al. Among authors: weissman d. J Control Release. 2015 Nov 10;217:345-51. doi: 10.1016/j.jconrel.2015.08.007. Epub 2015 Aug 8. J Control Release. 2015. PMID: 26264835 Free PMC article.

10

Nucleoside Modified mRNA Vaccines for Infectious Diseases.

Pardi N, Weissman D. Pardi N, et al. Among authors: weissman d. Methods Mol Biol. 2017;1499:109-121. doi: 10.1007/978-1-4939-6481-9_6. Methods Mol Biol. 2017. PMID: 27987145

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