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IMPDH inhibition activates TLR-VCAM1 pathway and suppresses the development of MLL-fusion leukemia.
Liu X, Sato N, Yabushita T, Li J, Jia Y, Tamura M, Asada S, Fujino T, Fukushima T, Yonezawa T, Tanaka Y, Fukuyama T, Tsuchiya A, Shikata S, Iwamura H, Kinouchi C, Komatsu K, Yamasaki S, Shibata T, Sasaki AT, Schibler J, Wunderlich M, O'Brien E, Mizukawa B, Mulloy JC, Sugiura Y, Takizawa H, Shibata T, Miyake K, Kitamura T, Goyama S. Liu X, et al. EMBO Mol Med. 2023 Jan 11;15(1):e15631. doi: 10.15252/emmm.202115631. Epub 2022 Dec 1. EMBO Mol Med. 2023. PMID: 36453131 Free PMC article.
The ubiquitin ligase STUB1 regulates stability and activity of RUNX1 and RUNX1-RUNX1T1.
Yonezawa T, Takahashi H, Shikata S, Liu X, Tamura M, Asada S, Fukushima T, Fukuyama T, Tanaka Y, Sawasaki T, Kitamura T, Goyama S. Yonezawa T, et al. Among authors: liu x. J Biol Chem. 2017 Jul 28;292(30):12528-12541. doi: 10.1074/jbc.M117.785675. Epub 2017 May 23. J Biol Chem. 2017. PMID: 28536267 Free PMC article.
Antitumor immunity augments the therapeutic effects of p53 activation on acute myeloid leukemia.
Hayashi Y, Goyama S, Liu X, Tamura M, Asada S, Tanaka Y, Fukuyama T, Wunderlich M, O'Brien E, Mizukawa B, Yamazaki S, Matsumoto A, Yamasaki S, Shibata T, Matsuda K, Sashida G, Takizawa H, Kitamura T. Hayashi Y, et al. Among authors: liu x. Nat Commun. 2019 Oct 25;10(1):4869. doi: 10.1038/s41467-019-12555-1. Nat Commun. 2019. PMID: 31653912 Free PMC article.
CHIP-associated mutant ASXL1 in blood cells promotes solid tumor progression.
Liu X, Sato N, Shimosato Y, Wang TW, Denda T, Chang YH, Yabushita T, Fujino T, Asada S, Tanaka Y, Fukuyama T, Enomoto Y, Ota Y, Sakamoto T, Kitamura T, Goyama S. Liu X, et al. Cancer Sci. 2022 Apr;113(4):1182-1194. doi: 10.1111/cas.15294. Epub 2022 Feb 26. Cancer Sci. 2022. PMID: 35133065 Free PMC article.
Clonal hematopoiesis-related mutant ASXL1 promotes atherosclerosis in mice via dysregulated innate immunity.
Sato N, Goyama S, Chang YH, Miyawaki M, Fujino T, Koide S, Denda T, Liu X, Ueda K, Yamamoto K, Asada S, Takeda R, Yonezawa T, Tanaka Y, Honda H, Ota Y, Shibata T, Sekiya M, Isobe T, Lamagna C, Masuda E, Iwama A, Shimano H, Inoue JI, Miyake K, Kitamura T. Sato N, et al. Among authors: liu x. Nat Cardiovasc Res. 2024 Dec;3(12):1568-1583. doi: 10.1038/s44161-024-00579-w. Epub 2024 Dec 9. Nat Cardiovasc Res. 2024. PMID: 39653824
Deep learning enhanced quantum holography with undetected photons.
Fan W, Qian G, Wang Y, Xu CR, Chen Z, Liu X, Li W, Liu X, Liu F, Xu X, Wang DW, Yakovlev VV. Fan W, et al. Among authors: liu x. Photonix. 2024;5(1):40. doi: 10.1186/s43074-024-00155-2. Epub 2024 Dec 18. Photonix. 2024. PMID: 39711807 Free PMC article.
Cell-type-resolved chromatin accessibility in the human intestine identifies complex regulatory programs and clarifies genetic associations in Crohn's disease.
Zhao Y, Zhou R, Mu Z, Carbonetto P, Zhong X, Xie B, Luo K, Cham CM, Koval J, He X, Dahl AW, Liu X, Chang EB, Basu A, Pott S. Zhao Y, et al. Among authors: liu x. medRxiv [Preprint]. 2024 Dec 11:2024.12.10.24318718. doi: 10.1101/2024.12.10.24318718. medRxiv. 2024. PMID: 39711713 Free PMC article. Preprint.
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