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Genome-wide data from medieval German Jews show that the Ashkenazi founder event pre-dated the 14th century.
Waldman S, Backenroth D, Harney É, Flohr S, Neff NC, Buckley GM, Fridman H, Akbari A, Rohland N, Mallick S, Olalde I, Cooper L, Lomes A, Lipson J, Cano Nistal J, Yu J, Barzilai N, Peter I, Atzmon G, Ostrer H, Lencz T, Maruvka YE, Lämmerhirt M, Beider A, Rutgers LV, Renson V, Prufer KM, Schiffels S, Ringbauer H, Sczech K, Carmi S, Reich D. Waldman S, et al. Among authors: lencz t. Cell. 2022 Dec 8;185(25):4703-4716.e16. doi: 10.1016/j.cell.2022.11.002. Epub 2022 Nov 30. Cell. 2022. PMID: 36455558 Free PMC article.
Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders.
Blokland GAM, Grove J, Chen CY, Cotsapas C, Tobet S, Handa R; Schizophrenia Working Group of the Psychiatric Genomics Consortium; St Clair D, Lencz T, Mowry BJ, Periyasamy S, Cairns MJ, Tooney PA, Wu JQ, Kelly B, Kirov G, Sullivan PF, Corvin A, Riley BP, Esko T, Milani L, Jönsson EG, Palotie A, Ehrenreich H, Begemann M, Steixner-Kumar A, Sham PC, Iwata N, Weinberger DR, Gejman PV, Sanders AR, Buxbaum JD, Rujescu D, Giegling I, Konte B, Hartmann AM, Bramon E, Murray RM, Pato MT, Lee J, Melle I, Molden E, Ophoff RA, McQuillin A, Bass NJ, Adolfsson R, Malhotra AK; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium; Martin NG, Fullerton JM, Mitchell PB, Schofield PR, Forstner AJ, Degenhardt F, Schaupp S, Comes AL, Kogevinas M, Guzman-Parra J, Reif A, Streit F, Sirignano L, Cichon S, Grigoroiu-Serbanescu M, Hauser J, Lissowska J, Mayoral F, Müller-Myhsok B, Świątkowska B, Schulze TG, Nöthen MM, Rietschel M, Kelsoe J, Leboyer M, Jamain S, Etain B, Bellivier F, Vincent JB, Alda M, O'Donovan C, Cervantes P, Biernacka JM, Frye M, McElroy SL, Scott LJ, Stahl EA, Landén M, Hamshere ML, Smeland OB, Djurovic S, Vaaler AE, Andreassen OA; Major Depressive Disorder Worki… See abstract for full author list ➔ Blokland GAM, et al. Among authors: lencz t. Biol Psychiatry. 2022 Jan 1;91(1):102-117. doi: 10.1016/j.biopsych.2021.02.972. Epub 2021 Mar 23. Biol Psychiatry. 2022. PMID: 34099189 Free PMC article.
Concerns about genetic risk testing for opioid use disorder.
Hatoum AS, Davis CN, Kember RL, Johnstone M, Oslin DW, Zinkstok JR, Burmeister M; Ethics, Position, and Public Policy Committee of the International Society of Psychiatric Genetics, Board of Directors of the International Society of Psychiatric Genetics; Agrawal A, Kranzler HR, Edenberg HJ, Gelernter J, Docherty AR, Lencz T. Hatoum AS, et al. Among authors: lencz t. Lancet Psychiatry. 2025 Feb;12(2):94-95. doi: 10.1016/S2215-0366(24)00310-9. Epub 2024 Oct 13. Lancet Psychiatry. 2025. PMID: 39413801 No abstract available.
The genetics of severe depression.
Franklin CE, Achtyes E, Altinay M, Bailey K, Bhati MT, Carr BR, Conroy SK, Husain MM, Khurshid KA, Lencz T, McDonald WM, Mickey BJ, Murrough J, Nestor S, Nickl-Jockschat T, Nikayin S, Reeves K, Reti IM, Selek S, Sanacora G, Trapp NT, Viswanath B, Wright JH, Sullivan P, Zandi PP, Potash JB. Franklin CE, et al. Among authors: lencz t. Mol Psychiatry. 2024 Oct 15. doi: 10.1038/s41380-024-02731-1. Online ahead of print. Mol Psychiatry. 2024. PMID: 39406997 Review.
Distinct genetic liability profiles define clinically relevant patient strata across common diseases.
Trastulla L, Dolgalev G, Moser S, Jiménez-Barrón LT, Andlauer TFM, von Scheidt M; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Budde M, Heilbronner U, Papiol S, Teumer A, Homuth G, Völzke H, Dörr M, Falkai P, Schulze TG, Gagneur J, Iorio F, Müller-Myhsok B, Schunkert H, Ziller MJ. Trastulla L, et al. Nat Commun. 2024 Jul 1;15(1):5534. doi: 10.1038/s41467-024-49338-2. Nat Commun. 2024. PMID: 38951512 Free PMC article.
256 results