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Loss of the volume-regulated anion channel components LRRC8A and LRRC8D limits platinum drug efficacy.
Widmer CA, Klebic I, Domanitskaya N, Decollogny M, Howald D, Siffert M, Essers P, Nowicka Z, Stokar-Regenscheit N, van de Ven M, de Korte-Grimmerink R, Galván JA, Pritchard CEJ, Huijbers IJ, Fendler W, Vens C, Rottenberg S. Widmer CA, et al. Cancer Res Commun. 2022 Oct 26;2(10):1266-1281. doi: 10.1158/2767-9764.CRC-22-0208. Cancer Res Commun. 2022. PMID: 36467895 Free PMC article.
PARPi, BRCA, and gaps: controversies and future research.
Dibitetto D, Widmer CA, Rottenberg S. Dibitetto D, et al. Among authors: widmer ca. Trends Cancer. 2024 Sep;10(9):857-869. doi: 10.1016/j.trecan.2024.06.008. Trends Cancer. 2024. PMID: 39004561 Free article. Review.