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Integration of genetic and chromatin modification data pinpoints autoimmune-specific remodeling of enhancer landscape in CD4+ T cells.
Daga N, Servaas NH, Kisand K, Moonen D, Arnold C, Reyes-Palomares A, Kaleviste E, Kingo K, Kuuse R, Ulst K, Steinmetz L, Peterson P, Nakic N, Zaugg JB. Daga N, et al. Among authors: servaas nh. Cell Rep. 2024 Oct 22;43(10):114810. doi: 10.1016/j.celrep.2024.114810. Epub 2024 Oct 9. Cell Rep. 2024. PMID: 39388354 Free article.
GRaNIE and GRaNPA: inference and evaluation of enhancer-mediated gene regulatory networks.
Kamal A, Arnold C, Claringbould A, Moussa R, Servaas NH, Kholmatov M, Daga N, Nogina D, Mueller-Dott S, Reyes-Palomares A, Palla G, Sigalova O, Bunina D, Pabst C, Zaugg JB. Kamal A, et al. Among authors: servaas nh. Mol Syst Biol. 2023 Jun 12;19(6):e11627. doi: 10.15252/msb.202311627. Epub 2023 Apr 19. Mol Syst Biol. 2023. PMID: 37073532 Free PMC article.
Nuclear Receptor Subfamily 4A Signaling as a Key Disease Pathway of CD1c+ Dendritic Cell Dysregulation in Systemic Sclerosis.
Servaas NH, Hiddingh S, Chouri E, Wichers CGK, Affandi AJ, Ottria A, Bekker CPJ, Cossu M, Silva-Cardoso SC, van der Kroef M, Hinrichs AC, Carvalheiro T, Vazirpanah N, Beretta L, Rossato M, Bonte-Mineur F, Radstake TRDJ, Kuiper JJW, Boes M, Pandit A. Servaas NH, et al. Arthritis Rheumatol. 2023 Feb;75(2):279-292. doi: 10.1002/art.42319. Epub 2022 Dec 8. Arthritis Rheumatol. 2023. PMID: 36482877 Free PMC article.
Angiopoietin-2 Promotes Inflammatory Activation in Monocytes of Systemic Sclerosis Patients.
Carvalheiro T, Lopes AP, van der Kroef M, Malvar-Fernandez B, Rafael-Vidal C, Hinrichs AC, Servaas NH, Bonte-Mineur F, Kok MR, Beretta L, Zimmermann M, Marut W, Pego-Reigosa JM, Radstake TRDJ, Garcia S. Carvalheiro T, et al. Among authors: servaas nh. Int J Mol Sci. 2020 Dec 15;21(24):9544. doi: 10.3390/ijms21249544. Int J Mol Sci. 2020. PMID: 33333969 Free PMC article.
Longitudinal analysis of T-cell receptor repertoires reveals persistence of antigen-driven CD4+ and CD8+ T-cell clusters in systemic sclerosis.
Servaas NH, Zaaraoui-Boutahar F, Wichers CGK, Ottria A, Chouri E, Affandi AJ, Silva-Cardoso S, van der Kroef M, Carvalheiro T, van Wijk F, Radstake TRDJ, Andeweg AC, Pandit A. Servaas NH, et al. J Autoimmun. 2021 Feb;117:102574. doi: 10.1016/j.jaut.2020.102574. Epub 2020 Dec 8. J Autoimmun. 2021. PMID: 33307312 Free article.
Plasmacytoid DCs From Patients With Sjögren's Syndrome Are Transcriptionally Primed for Enhanced Pro-inflammatory Cytokine Production.
Hillen MR, Pandit A, Blokland SLM, Hartgring SAY, Bekker CPJ, van der Heijden EHM, Servaas NH, Rossato M, Kruize AA, van Roon JAG, Radstake TRDJ. Hillen MR, et al. Among authors: servaas nh. Front Immunol. 2019 Sep 4;10:2096. doi: 10.3389/fimmu.2019.02096. eCollection 2019. Front Immunol. 2019. PMID: 31552042 Free PMC article.
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