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Nanobody-based CD38-specific heavy chain antibodies induce killing of multiple myeloma and other hematological malignancies.
Schriewer L, Schütze K, Petry K, Hambach J, Fumey W, Koenigsdorf J, Baum N, Menzel S, Rissiek B, Riecken K, Fehse B, Röckendorf JL, Schmid J, Albrecht B, Pinnschmidt H, Ayuk F, Kröger N, Binder M, Schuch G, Hansen T, Haag F, Adam G, Koch-Nolte F, Bannas P. Schriewer L, et al. Among authors: schutze k. Theranostics. 2020 Feb 3;10(6):2645-2658. doi: 10.7150/thno.38533. eCollection 2020. Theranostics. 2020. PMID: 32194826 Free PMC article.
Molecular imaging of tumors with nanobodies and antibodies: Timing and dosage are crucial factors for improved in vivo detection.
Bannas P, Lenz A, Kunick V, Well L, Fumey W, Rissiek B, Haag F, Schmid J, Schütze K, Eichhoff A, Trepel M, Adam G, Ittrich H, Koch-Nolte F. Bannas P, et al. Among authors: schutze k. Contrast Media Mol Imaging. 2015 Sep-Oct;10(5):367-78. doi: 10.1002/cmmi.1637. Epub 2015 Apr 27. Contrast Media Mol Imaging. 2015. PMID: 25925493 Free article.
Long-term CD38 saturation by daratumumab interferes with diagnostic myeloma cell detection.
Oberle A, Brandt A, Alawi M, Langebrake C, Janjetovic S, Wolschke C, Schütze K, Bannas P, Kröger N, Koch-Nolte F, Bokemeyer C, Binder M. Oberle A, et al. Among authors: schutze k. Haematologica. 2017 Sep;102(9):e368-e370. doi: 10.3324/haematol.2017.169235. Epub 2017 May 18. Haematologica. 2017. PMID: 28522580 Free PMC article. No abstract available.
Nanobodies effectively modulate the enzymatic activity of CD38 and allow specific imaging of CD38+ tumors in mouse models in vivo.
Fumey W, Koenigsdorf J, Kunick V, Menzel S, Schütze K, Unger M, Schriewer L, Haag F, Adam G, Oberle A, Binder M, Fliegert R, Guse A, Zhao YJ, Cheung Lee H, Malavasi F, Goldbaum F, van Hegelsom R, Stortelers C, Bannas P, Koch-Nolte F. Fumey W, et al. Among authors: schutze k. Sci Rep. 2017 Oct 30;7(1):14289. doi: 10.1038/s41598-017-14112-6. Sci Rep. 2017. PMID: 29084989 Free PMC article.
Molecular Display of the Animal Meta-Venome for Discovery of Novel Therapeutic Peptides.
Hsiao MH, Miao Y, Liu Z, Schütze K, Limjunyawong N, Chun-Che Chien D, Monteiro WD, Chu LS, Morgenlander W, Jayaraman S, Jang SE, Gray JJ, Zhu H, Dong X, Steinegger M, Larman HB. Hsiao MH, et al. Among authors: schutze k. Mol Cell Proteomics. 2024 Dec 31:100901. doi: 10.1016/j.mcpro.2024.100901. Online ahead of print. Mol Cell Proteomics. 2024. PMID: 39746545 Free article.
154 results