Bai R - Search Results

1

RS6077 induces mitotic arrest and selectively activates cell death in human cancer cell lines and in a lymphoma tumor in vivo.

Sebastiani J, Puxeddu M, Nalli M, Bai R, Altieri L, Rovella P, Gaudio E, Trisciuoglio D, Spriano F, Lavia P, Fionda C, Masci D, Urbani A, Bigogno C, Dondio G, Hamel E, Bertoni F, Silvestri R, La Regina G. Sebastiani J, et al. Among authors: bai r. Eur J Med Chem. 2023 Jan 15;246:114997. doi: 10.1016/j.ejmech.2022.114997. Epub 2022 Dec 5. Eur J Med Chem. 2023. PMID: 36502578

2

(-)-Doliculide, a new macrocyclic depsipeptide enhancer of actin assembly.

Bai R, Covell DG, Liu C, Ghosh AK, Hamel E. Bai R, et al. J Biol Chem. 2002 Aug 30;277(35):32165-71. doi: 10.1074/jbc.M205076200. Epub 2002 Jun 20. J Biol Chem. 2002. PMID: 12077149 Free article.

3

Lyngbyastatin 1 and Ibu-epilyngbyastatin 1: synthesis, stereochemistry, and NMR line broadening.

Bai R, Bates RB, Hamel E, Moore RE, Nakkiew P, Pettit GR, Sufi BA. Bai R, et al. J Nat Prod. 2002 Dec;65(12):1824-9. doi: 10.1021/np020117w. J Nat Prod. 2002. PMID: 12502322

4

Diazonamide A and a synthetic structural analog: disruptive effects on mitosis and cellular microtubules and analysis of their interactions with tubulin.

Cruz-Monserrate Z, Vervoort HC, Bai R, Newman DJ, Howell SB, Los G, Mullaney JT, Williams MD, Pettit GR, Fenical W, Hamel E. Cruz-Monserrate Z, et al. Among authors: bai r. Mol Pharmacol. 2003 Jun;63(6):1273-80. doi: 10.1124/mol.63.6.1273. Mol Pharmacol. 2003. PMID: 12761336

5

Synthesis, cytotoxicity, and inhibitory effects on tubulin polymerization of a new 3-heterocyclo substituted 2-styrylquinazolinones.

Raffa D, Edler MC, Daidone G, Maggio B, Merikech M, Plescia S, Schillaci D, Bai R, Hamel E. Raffa D, et al. Among authors: bai r. Eur J Med Chem. 2004 Apr;39(4):299-304. doi: 10.1016/j.ejmech.2003.12.009. Eur J Med Chem. 2004. PMID: 15072839

6

Direct photoaffinity labeling by dolastatin 10 of the amino-terminal peptide of beta-tubulin containing cysteine 12.

Bai R, Covell DG, Taylor GF, Kepler JA, Copeland TD, Nguyen NY, Pettit GR, Hamel E. Bai R, et al. J Biol Chem. 2004 Jul 16;279(29):30731-40. doi: 10.1074/jbc.M402110200. Epub 2004 Apr 29. J Biol Chem. 2004. PMID: 15123603 Free article.

7

Laulimalide and paclitaxel: a comparison of their effects on tubulin assembly and their synergistic action when present simultaneously.

Gapud EJ, Bai R, Ghosh AK, Hamel E. Gapud EJ, et al. Among authors: bai r. Mol Pharmacol. 2004 Jul;66(1):113-21. doi: 10.1124/mol.66.1.113. Mol Pharmacol. 2004. PMID: 15213302

8

Total synthesis and biological evaluation of ustiloxin natural products and two analogs.

Li P, Evans CD, Forbeck EM, Park H, Bai R, Hamel E, Joullié MM. Li P, et al. Among authors: bai r. Bioorg Med Chem Lett. 2006 Sep 15;16(18):4804-7. doi: 10.1016/j.bmcl.2006.06.071. Epub 2006 Jul 11. Bioorg Med Chem Lett. 2006. PMID: 16837194

9

Comparison of the activities of the truncated halichondrin B analog NSC 707389 (E7389) with those of the parent compound and a proposed binding site on tubulin.

Dabydeen DA, Burnett JC, Bai R, Verdier-Pinard P, Hickford SJ, Pettit GR, Blunt JW, Munro MH, Gussio R, Hamel E. Dabydeen DA, et al. Among authors: bai r. Mol Pharmacol. 2006 Dec;70(6):1866-75. doi: 10.1124/mol.106.026641. Epub 2006 Aug 29. Mol Pharmacol. 2006. PMID: 16940412

10

Interaction of a cyclostreptin analogue with the microtubule taxoid site: the covalent reaction rapidly follows binding.

Bai R, Vanderwal CD, Díaz JF, Hamel E. Bai R, et al. J Nat Prod. 2008 Mar;71(3):370-4. doi: 10.1021/np800056m. Epub 2008 Feb 26. J Nat Prod. 2008. PMID: 18298077

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