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Single-cell analysis of senescent epithelia reveals targetable mechanisms promoting fibrosis.
O'Sullivan ED, Mylonas KJ, Bell R, Carvalho C, Baird DP, Cairns C, Gallagher KM, Campbell R, Docherty M, Laird A, Henderson NC, Chandra T, Kirschner K, Conway B, Dihazi GH, Zeisberg M, Hughes J, Denby L, Dihazi H, Ferenbach DA. O'Sullivan ED, et al. Among authors: carvalho c. JCI Insight. 2022 Nov 22;7(22):e154124. doi: 10.1172/jci.insight.154124. JCI Insight. 2022. PMID: 36509292 Free PMC article.
Histone variant H2A.J accumulates in senescent cells and promotes inflammatory gene expression.
Contrepois K, Coudereau C, Benayoun BA, Schuler N, Roux PF, Bischof O, Courbeyrette R, Carvalho C, Thuret JY, Ma Z, Derbois C, Nevers MC, Volland H, Redon CE, Bonner WM, Deleuze JF, Wiel C, Bernard D, Snyder MP, Rübe CE, Olaso R, Fenaille F, Mann C. Contrepois K, et al. Among authors: carvalho c. Nat Commun. 2017 May 10;8:14995. doi: 10.1038/ncomms14995. Nat Commun. 2017. PMID: 28489069 Free PMC article.
Glucocorticoids delay RAF-induced senescence promoted by EGR1.
Carvalho C, L'Hôte V, Courbeyrette R, Kratassiouk G, Pinna G, Cintrat JC, Denby-Wilkes C, Derbois C, Olaso R, Deleuze JF, Mann C, Thuret JY. Carvalho C, et al. J Cell Sci. 2019 Aug 22;132(16):jcs230748. doi: 10.1242/jcs.230748. J Cell Sci. 2019. PMID: 31371485
GREGoR: Accelerating Genomics for Rare Diseases.
Dawood M, Heavner B, Wheeler MM, Ungar RA, LoTempio J, Wiel L, Berger S, Bernstein JA, Chong JX, Délot EC, Eichler EE, Gibbs RA, Lupski JR, Shojaie A, Talkowski ME, Wagner AH, Wei CL, Wellington C, Wheeler MT, Members GP, Carvalho CMB, Gifford CA, May S, Miller DE, Rehm HL, Sedlazeck FJ, Vilain E, O'Donnell-Luria A, Posey JE, Chadwick LH, Bamshad MJ, Montgomery SB, Diseases GRTETGOR, Consortium. Dawood M, et al. Among authors: carvalho cmb. ArXiv [Preprint]. 2024 Dec 18:arXiv:2412.14338v1. ArXiv. 2024. PMID: 39764392 Free PMC article. Preprint.
Circulating miR-134 in mesial temporal lobe epilepsy: implications in hippocampal sclerosis development and drug resistance.
Guerra Leal B, Carvalho C, Santos C, Samões R, Martins-Ferreira R, Teixeira C, Rodrigues D, Freitas J, Lemos C, Chorão R, Ramalheira J, Lopes J, Martins da Silva A, Pinho E Costa P, Chaves J. Guerra Leal B, et al. Among authors: carvalho c. Front Mol Neurosci. 2024 Dec 18;17:1512860. doi: 10.3389/fnmol.2024.1512860. eCollection 2024. Front Mol Neurosci. 2024. PMID: 39744540 Free PMC article.
Genetic modulation of RNA splicing rescues BRCA2 function in mutant cells.
Lima BA, Pais AC, Dupont J, Dias P, Custódio N, Sousa AB, Carmo-Fonseca M, Carvalho C. Lima BA, et al. Among authors: carvalho c. Life Sci Alliance. 2024 Dec 31;8(3):e202402845. doi: 10.26508/lsa.202402845. Print 2025 Mar. Life Sci Alliance. 2024. PMID: 39741007 Free PMC article.
3,198 results