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Single-cell analysis of senescent epithelia reveals targetable mechanisms promoting fibrosis.
O'Sullivan ED, Mylonas KJ, Bell R, Carvalho C, Baird DP, Cairns C, Gallagher KM, Campbell R, Docherty M, Laird A, Henderson NC, Chandra T, Kirschner K, Conway B, Dihazi GH, Zeisberg M, Hughes J, Denby L, Dihazi H, Ferenbach DA. O'Sullivan ED, et al. Among authors: henderson nc. JCI Insight. 2022 Nov 22;7(22):e154124. doi: 10.1172/jci.insight.154124. JCI Insight. 2022. PMID: 36509292 Free PMC article.
Acute Liver Injury Is Independent of B Cells or Immunoglobulin M.
Richards JA, Bucsaiova M, Hesketh EE, Ventre C, Henderson NC, Simpson K, Bellamy CO, Howie SE, Anderton SM, Hughes J, Wigmore SJ. Richards JA, et al. Among authors: henderson nc. PLoS One. 2015 Sep 25;10(9):e0138688. doi: 10.1371/journal.pone.0138688. eCollection 2015. PLoS One. 2015. PMID: 26406765 Free PMC article.
Unravelling fibrosis using single-cell transcriptomics.
Dobie R, Henderson NC. Dobie R, et al. Among authors: henderson nc. Curr Opin Pharmacol. 2019 Dec;49:71-75. doi: 10.1016/j.coph.2019.09.004. Epub 2019 Oct 25. Curr Opin Pharmacol. 2019. PMID: 31670054 Free article. Review.
Stromal Cells Covering Omental Fat-Associated Lymphoid Clusters Trigger Formation of Neutrophil Aggregates to Capture Peritoneal Contaminants.
Jackson-Jones LH, Smith P, Portman JR, Magalhaes MS, Mylonas KJ, Vermeren MM, Nixon M, Henderson BEP, Dobie R, Vermeren S, Denby L, Henderson NC, Mole DJ, Bénézech C. Jackson-Jones LH, et al. Among authors: henderson nc, henderson bep. Immunity. 2020 Apr 14;52(4):700-715.e6. doi: 10.1016/j.immuni.2020.03.011. Immunity. 2020. PMID: 32294409 Free PMC article.
Kidney Single-Cell Atlas Reveals Myeloid Heterogeneity in Progression and Regression of Kidney Disease.
Conway BR, O'Sullivan ED, Cairns C, O'Sullivan J, Simpson DJ, Salzano A, Connor K, Ding P, Humphries D, Stewart K, Teenan O, Pius R, Henderson NC, Bénézech C, Ramachandran P, Ferenbach D, Hughes J, Chandra T, Denby L. Conway BR, et al. Among authors: henderson nc. J Am Soc Nephrol. 2020 Dec;31(12):2833-2854. doi: 10.1681/ASN.2020060806. Epub 2020 Sep 25. J Am Soc Nephrol. 2020. PMID: 32978267 Free PMC article.
Decoding myofibroblast origins in human kidney fibrosis.
Kuppe C, Ibrahim MM, Kranz J, Zhang X, Ziegler S, Perales-Patón J, Jansen J, Reimer KC, Smith JR, Dobie R, Wilson-Kanamori JR, Halder M, Xu Y, Kabgani N, Kaesler N, Klaus M, Gernhold L, Puelles VG, Huber TB, Boor P, Menzel S, Hoogenboezem RM, Bindels EMJ, Steffens J, Floege J, Schneider RK, Saez-Rodriguez J, Henderson NC, Kramann R. Kuppe C, et al. Among authors: henderson nc. Nature. 2021 Jan;589(7841):281-286. doi: 10.1038/s41586-020-2941-1. Epub 2020 Nov 11. Nature. 2021. PMID: 33176333 Free PMC article.
Transfer of hepatocellular microRNA regulates cytochrome P450 2E1 in renal tubular cells.
Matthews O, Morrison EE, Tranter JD, Starkey Lewis P, Toor IS, Srivastava A, Sargeant R, Rollison H, Matchett KP, Kendall TJ, Gray GA, Goldring C, Park K, Denby L, Dhaun N, Bailey MA, Henderson NC, Williams D, Dear JW. Matthews O, et al. Among authors: henderson nc. EBioMedicine. 2020 Dec;62:103092. doi: 10.1016/j.ebiom.2020.103092. Epub 2020 Nov 21. EBioMedicine. 2020. PMID: 33232872 Free PMC article.
Fibrosis: from mechanisms to medicines.
Henderson NC, Rieder F, Wynn TA. Henderson NC, et al. Nature. 2020 Nov;587(7835):555-566. doi: 10.1038/s41586-020-2938-9. Epub 2020 Nov 25. Nature. 2020. PMID: 33239795 Free PMC article. Review.
141 results